Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25032062 | 1.00 | RORC (0.40) | RORCCYP19A1PDE4APDE4BPDE4C | |
| SCHEMBL25032061 | 0.86 | PDE5A (0.43) | RORCALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL25032058 | 0.79 | PTGS2 (0.40) | RORCPTGS2PTGS1KMT2APDE5A | |
| SCHEMBL25033635 | 0.77 | MEN1 (0.32) | CYP19A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25032067 | 0.77 | KMT2A (0.40) | RORCPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25032060 | 0.75 | MAPT (0.32) | RORCCYP19A1PDE4APDE4BPDE4C | |
| SCHEMBL25033211 | 0.75 | TOP2B (0.48) | PTGS2ALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL23625080 | 0.73 | CYP19A1 (0.38) | RORCCYP19A1PDE4APDE4BPDE4C | |
| SCHEMBL25033617 | 0.72 | PTGS2 (0.42) | CYP19A1PTGS2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL25032074 | 0.72 | KMT2A (0.40) | PTGS2ALDH1A1MAPTMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |