Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CFB | P00751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29212439 | 0.78 | CA12 (0.37) | CA12CA9CA1CA2 | |
| SCHEMBL30184459 | 0.72 | NR3C1 (0.51) | — | |
| SCHEMBL29212355 | 0.72 | NR3C1 (0.51) | — | |
| SCHEMBL806532 | 0.70 | CFB (0.40) | CFB | |
| SCHEMBL19186982 | 0.70 | AXL (0.31) | — | |
| SCHEMBL24762611 | 0.70 | PABPC1 (0.33) | — | |
| SCHEMBL25667793 | 0.69 | BTK (0.46) | CA9CA1CA2 | |
| SCHEMBL24872829 | 0.65 | OPRK1 (0.39) | CFB | |
| SCHEMBL24762761 | 0.65 | MAPT (0.46) | CA12CA9CA1CA2 | |
| SCHEMBL20350309 | 0.65 | ALDH1A1 (0.36) | CFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |