Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 5/20 | 0.50 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27354682 | 0.96 | CTSB (0.48) | CTSSCTSLCTSBMMEACE | |
| SCHEMBL24158538 | 0.87 | ACE (0.49) | CTSSCTSLCTSBMMEACE | |
| SCHEMBL24183746 | 0.85 | OPRD1 (0.45) | CTSSCTSLCTSBCTSKOPRD1 | |
| SCHEMBL3495410 | 0.85 | ACE (0.57) | MMEACEECE1 | |
| SCHEMBL26154352 | 0.85 | REN (0.45) | CTSSCTSLCTSBCTSKOPRD1 | |
| SCHEMBL7587101 | 0.82 | CTSS (0.54) | CTSSCTSLCTSBMMEACE | |
| SCHEMBL1848846 | 0.82 | CTSS (0.54) | CTSSCTSLCTSBMMEACE | |
| SCHEMBL30051602 | 0.82 | CTSS (0.54) | CTSSCTSLCTSBMMEACE | |
| SCHEMBL24158317 | 0.82 | NPC1 (0.46) | CTSSCTSLCTSBACEALDH1A1 | |
| SCHEMBL6474029 | 0.82 | OPRD1 (0.64) | CTSSCTSLCTSBMMEOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016488-A1 | MICROTUBULE INHIBITOR-BASED ANTIBODY-DRUG CONJUGATE | 昆山新蕴达生物科技有限公司 | 2023-02-16 | — | — | WO | disclosed |