Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356546 | 0.78 | AURKA (0.43) | PRMT5WDR77MKNK2SRCKDR | |
| SCHEMBL25047374 | 0.78 | HCAR1 (0.34) | LCKSRCKDRTEKHCAR1 | |
| SCHEMBL2241217 | 0.78 | MKNK2 (0.41) | PRMT5WDR77MKNK2SRCKDR | |
| SCHEMBL25958441 | 0.77 | AURKA (0.44) | PRMT5WDR77MKNK2SRCKDR | |
| SCHEMBL28122201 | 0.75 | ABL1 (0.42) | PRMT5WDR77MKNK2NNMTLCK | |
| SCHEMBL24109809 | 0.74 | NNMT (0.37) | PRMT5WDR77MKNK2NNMTIRAK4 | |
| SCHEMBL29485663 | 0.73 | ADK (0.45) | PRMT5WDR77 | |
| SCHEMBL937901 | 0.73 | UBA6 (0.49) | PRMT5WDR77MKNK2NNMTIRAK4 | |
| SCHEMBL937900 | 0.73 | MKNK2 (0.37) | PRMT5WDR77MKNK2NNMTMKNK1 | |
| SCHEMBL25047326 | 0.72 | ALDH1A1 (0.46) | PRMT5WDR77MKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |