Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 4/20 | 0.38 |
| ▸ | JAK3 | P52333 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20049565 | 0.83 | PDPK1 (0.39) | JAK1JAK3JAK2GPR119ADCY5 | |
| SCHEMBL20049536 | 0.79 | PDPK1 (0.36) | JAK1JAK3JAK2GPR119ADCY5 | |
| SCHEMBL29743109 | 0.77 | PRMT5 (0.34) | JAK1JAK3JAK2PRMT5WDR77 | |
| SCHEMBL25047420 | 0.77 | PRMT5 (0.34) | JAK1JAK3JAK2PRMT5WDR77 | |
| SCHEMBL23892580 | 0.76 | GPR119 (0.33) | JAK1JAK3JAK2GPR119PRMT5 | |
| SCHEMBL25949326 | 0.75 | GPR119 (0.33) | JAK1JAK3JAK2GPR119 | |
| SCHEMBL23137091 | 0.75 | JAK2 (0.31) | JAK1JAK3JAK2GPR119 | |
| SCHEMBL19714858 | 0.75 | PDPK1 (0.40) | JAK1JAK3JAK2GPR119ADCY5 | |
| SCHEMBL25046560 | 0.74 | ADK (0.41) | PRMT5WDR77 | |
| SCHEMBL25047848 | 0.73 | ADK (0.50) | ADCY5PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |