Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046703 | 0.89 | PDE2A (0.37) | PDE2AHTR2BADORA3ADORA2AADORA1 | |
| SCHEMBL25048345 | 0.84 | CHKA (0.35) | ADORA3ADORA2AADORA1ESR2ESR1 | |
| SCHEMBL25048154 | 0.82 | PDE2A (0.36) | PDE2AHTR2BADORA3ADORA2AADORA1 | |
| SCHEMBL25049253 | 0.78 | ADORA3 (0.38) | PDE2AGAAHTR2BADORA3ADORA2A | |
| SCHEMBL25049211 | 0.74 | NPBWR1 (0.35) | PIP4K2A | |
| SCHEMBL25048741 | 0.74 | OPRM1 (0.38) | OPRM1 | |
| SCHEMBL25046781 | 0.72 | CHKA (0.38) | — | |
| SCHEMBL25046755 | 0.70 | PDE10A (0.32) | — | |
| SCHEMBL25048803 | 0.69 | PIP4K2A (0.35) | GAAPIP4K2A | |
| SCHEMBL25047669 | 0.68 | CHKA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |