Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24548283 | 0.85 | TK1 (0.50) | TK1 | |
| SCHEMBL12595723 | 0.84 | TK1 (0.56) | TK1POLB | |
| SCHEMBL6364862 | 0.81 | TK2 (0.47) | TK1 | |
| SCHEMBL21246468 | 0.78 | BCHE (0.55) | TK1 | |
| SCHEMBL6370075 | 0.76 | TK2 (0.43) | TK1 | |
| SCHEMBL25966495 | 0.75 | TK1 (0.52) | TK1POLB | |
| SCHEMBL2158702 | 0.74 | LMNA (0.55) | TK1POLB | |
| SCHEMBL14232397 | 0.74 | LMNA (0.55) | TK1POLB | |
| SCHEMBL12596285 | 0.73 | LMNA (0.48) | TK1 | |
| SCHEMBL933552 | 0.73 | LMNA (0.54) | TK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054720-A1 | Antisense Oligonucleotides Targeting ATXN3 | HOFFMANN-LA ROCHE INC. | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054720-A1 | Antisense Oligonucleotides Targeting ATXN3 | ATXN2, ATXN2L, ATXN10 | TK1 891/4885POLB 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.