Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 7/20 | 0.47 |
| ▸ | TK1 | P04183 | 9/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370075 | 0.94 | TK2 (0.43) | TK2TK1HSP90AA1RNASE1 | |
| SCHEMBL14638734 | 0.83 | TYMP (0.43) | TK2TK1RNASE1 | |
| SCHEMBL25061415 | 0.81 | TK1 (0.47) | TK1 | |
| SCHEMBL6328992 | 0.80 | RNASE1 (0.52) | TK2TK1RNASE1 | |
| SCHEMBL1727320 | 0.80 | POLB (0.58) | TK1 | |
| SCHEMBL10446716 | 0.80 | POLB (0.58) | TK1 | |
| SCHEMBL6328988 | 0.80 | RNASE1 (0.52) | TK2TK1RNASE1 | |
| SCHEMBL8189618 | 0.80 | RNASE1 (0.52) | TK2TK1RNASE1 | |
| SCHEMBL6334503 | 0.80 | POLB (0.58) | TK1 | |
| SCHEMBL7746722 | 0.80 | RNASE1 (0.52) | TK2TK1RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176941-A1 | Nucleoside analogues whose sugar moieties are bound in s-form and oligonucleotide derivatives comprising nucleotide analogues thereof | TAKESHI IMANISHI (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1486504-A1 | NUCLEOSIDE ANALOGUES WHOSE SUGAR MOIETIES ARE BOUND IN S-FORM AND OLIGONUCLEOTIDE DERIVATIVES COMPRISING NUCLEOTIDE ANALOGUES THEREOF | Imanishi, Takeshi (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176941-A1 | Nucleoside analogues whose sugar moieties are bound in s-form and oligonucleotide derivatives comprising nucleotide analogues thereof | RNGTT, NSUN2, SNRPE | TK2 1101/4885TK1 259/4885HSP90AA1 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.