Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25062005 | 0.83 | LMNA (0.58) | TDP1KMT2AHSD11B1CA1CA2 | |
| SCHEMBL25061946 | 0.80 | NPC1 (0.49) | KMT2AHSD11B1NPC1ALDH1A1TSHR | |
| SCHEMBL28727247 | 0.79 | HSD11B1 (0.54) | TDP1KMT2AHSD11B1CA9ALDH1A1 | |
| SCHEMBL24390169 | 0.79 | HSD11B1 (0.46) | TDP1KMT2AHSD11B1NPC1RAB9A | |
| SCHEMBL25061967 | 0.79 | KDM4E (0.48) | TDP1HSD11B1ALDH1A1 | |
| SCHEMBL25061924 | 0.78 | HSD11B1 (0.49) | KMT2AHSD11B1ALDH1A1TP53GLA | |
| SCHEMBL25061975 | 0.78 | MAPK1 (0.49) | KMT2AHSD11B1ALDH1A1TP53MAPK1 | |
| SCHEMBL29234755 | 0.78 | HSD11B1 (0.47) | KMT2AHSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL25061925 | 0.78 | HSD11B1 (0.45) | KMT2AHSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL2024141 | 0.78 | KMT2A (0.73) | KMT2AHSD11B1RAB9ACA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054928-A1 | METHOD FOR PREPARING CARBONYL SULFONE | SOOCHOW UNIVERSITY (CN) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054928-A1 | METHOD FOR PREPARING CARBONYL SULFONE | TST, CBS, STS | TDP1 3672/4885KMT2A 2093/4885APP 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.