Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25062003 | 0.78 | TDP1 (0.54) | HSD11B1KMT2ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL28727247 | 0.77 | HSD11B1 (0.54) | HSD11B1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL25061924 | 0.76 | HSD11B1 (0.49) | HSD11B1KMT2APOLBGAAMMP2 | |
| SCHEMBL25061975 | 0.76 | MAPK1 (0.49) | HSD11B1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL29234755 | 0.76 | HSD11B1 (0.47) | HSD11B1KMT2APOLBSMN1; SMN2GAA | |
| SCHEMBL2024141 | 0.76 | KMT2A (0.73) | HSD11B1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL14456209 | 0.75 | TSHR (0.53) | HSD11B1KMT2APOLBSMN1; SMN2GAA | |
| SCHEMBL11057726 | 0.75 | TSHR (0.53) | HSD11B1KMT2APOLBSMN1; SMN2GAA | |
| SCHEMBL5093364 | 0.75 | TSHR (0.53) | HSD11B1KMT2APOLBSMN1; SMN2GAA | |
| SCHEMBL25062005 | 0.74 | LMNA (0.58) | HSD11B1KMT2AGAAMMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054928-A1 | METHOD FOR PREPARING CARBONYL SULFONE | SOOCHOW UNIVERSITY (CN) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054928-A1 | METHOD FOR PREPARING CARBONYL SULFONE | TST, CBS, STS | HSD11B1 1197/4885KMT2A 2093/4885POLB 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.