SCHEMBL2511249

SCHEMBL2511249

CCCC(CCC)[PH](=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.38
AKR1A1 P14550 1/20 0.38
CHRM3 P20309 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 3/20 0.36
CYP3A4 P08684 2/20 0.36
NFKB1 P19838 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
FDPS P14324 1/20 0.36
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28343151 0.97 CHRM1 (0.36) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL2517912 0.97 CHRM1 (0.36) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL16163212 0.90 FDPS (0.43) TSHRFDPS
SCHEMBL940772 0.89
SCHEMBL25405199 0.88 FDPS (0.41) TSHRFDPS
SCHEMBL16163021 0.88 FDPS (0.45) FDPSLMNA
SCHEMBL29120177 0.87 LMNA (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL4772203 0.87 LMNA (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL28120332 0.87 LMNA (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL28086698 0.87 LMNA (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778359-B Dialkyl phosphinate and preparation method and application thereof 浙江新化化工股份有限公司 2022-09-16 CN claimed
CN-112778359-A Dialkyl phosphinate and preparation method and application thereof 浙江新化化工股份有限公司 2021-05-11 CN claimed
EP-2794623-B1 MIXTURES OF AT LEAST ONE DIALKYLPHOSPHINIC ACID WITH AT LEAST ONE OTHER DIALKYLPHOSPHINIC ACID THAT IS DIFFERENT THEREFROM, METHOD FOR PRODUCTION THEREOF, AND USE THEREOF CLARIANT INT LTD (CH) 2017-10-18 EP claimed
EP-2791151-B1 MIXTURES OF DIALKYLPHOSPHINIC ACIDS AND ALKYLPHOSPHONIC ACIDS, A PROCESS FOR PREPARATION THEREOF AND USE THEREOF CLARIANT INT LTD (CH) 2016-09-07 EP claimed
US-20140350149-A1 Mixtures Of At Least One Dialkylphosphinic Acid With At Least One Other Dialkylphosphinic Acid That Is Different Therefrom, Method For Production Thereof, And Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-11-27 US claimed
US-20140309340-A1 Mixtures Of Dialkylphosphinic Acids And Alkylphosphinic Acids, A Process For Preparation Thereof And Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-10-16 US claimed
CN-118562063-A Liquid composition comprising a phosphorus-based additive, use thereof and material or composition obtained after polymerization of the composition 阿肯马法国公司 2024-08-30 CN disclosed
CN-116745025-A membrane for water filtration 水通道蛋白有限公司 2023-09-12 CN disclosed
US-11629212-B2 Liquid composition comprising a phousphorus based additive, its use and material or composition obtained following polymerisation of composition ARKEMA FRANCE (FR) 2023-04-18 US disclosed
CN-112778359-B Dialkyl phosphinate and preparation method and application thereof 浙江新化化工股份有限公司 2022-09-16 CN disclosed
CN-112778359-A Dialkyl phosphinate and preparation method and application thereof 浙江新化化工股份有限公司 2021-05-11 CN disclosed
EP-3744743-A1 LIQUID COMPOSITION COMPRISING A PHOSPHORUS BASED ADDITIVE, ITS USE AND MATERIAL OR COMPOSITION OBTAINED FOLLOWING POLYMERISATION OF COMPOSTION ARKEMA FRANCE (FR) 2020-12-02 EP disclosed
EP-3481875-B1 LIQUID COMPOSITION COMPRISING A PHOUSPHORUS BASED ADDITIVE, ITS USE AND MATERIAL OR COMPOSITION OBTAINED FOLLOWING POLYMERISATION OF COMPOSITION ARKEMA FRANCE (FR) 2020-04-08 EP disclosed
US-10246640-B2 Mixtures of at least one dialkylphosphinic acid with at least one other dialkylphosphinic acid that is different therefrom, method for production thereof, and use thereof CLARIANT INTERNATIONAL LTD. (CH) 2019-04-02 US disclosed
US-10106744-B2 Mixtures of dialkylphosphinic acids and alkylphosphinic acids, a process for preparation thereof and use thereof CLARIANT INTERNATIONAL LTD. (CH) 2018-10-23 US disclosed
WO-2018011193-A1 LIQUID COMPOSITION COMPRISING A PHOUSPHORUS BASED ADDITIVE, ITS USE AND MATERIAL OR COMPOSITION OBTAINED FOLLOWING POLYMERISATION OF COMPOSTION ARKEMA FRANCE (FR) 2018-01-18 WO disclosed
US-20180010047-A1 Mixtures Of At Least One Dialkylphosphinic Acid With At Least One Other Dialkylphosphinic Acid That Is Different Therefrom, Method For Production Thereof, And Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2018-01-11 US disclosed
US-20140350149-A1 Mixtures Of At Least One Dialkylphosphinic Acid With At Least One Other Dialkylphosphinic Acid That Is Different Therefrom, Method For Production Thereof, And Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-11-27 US disclosed
US-20140309340-A1 Mixtures Of Dialkylphosphinic Acids And Alkylphosphinic Acids, A Process For Preparation Thereof And Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-10-16 US disclosed
US-20110245386-A1 Method for the Production of Mixed-Substituted Dialkylphosphinic Acids, Esters, and Salts, and Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2011-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10106744-B2 Mixtures of dialkylphosphinic acids and alkylphosphinic acids, a process for preparation thereof and use thereof C3AR1, ENPP2, AKR1C3 CHRM1 998/4885AKR1A1 68/4885CHRM3 1448/4885
US-10246640-B2 Mixtures of at least one dialkylphosphinic acid with at least one other dialkylphosphinic acid that is different therefrom, method for production thereof, and use thereof CYP27A1, CYP21A2, CYP46A1 CHRM1 775/4885AKR1A1 27/4885CHRM3 1123/4885
US-20180010047-A1 Mixtures Of At Least One Dialkylphosphinic Acid With At Least One Other Dialkylphosphinic Acid That Is Different Therefrom, Method For Production Thereof, And Use Thereof CYP21A2, CYP27A1, CYP46A1 CHRM1 490/4885AKR1A1 24/4885CHRM3 690/4885
US-20110245386-A1 Method for the Production of Mixed-Substituted Dialkylphosphinic Acids, Esters, and Salts, and Use Thereof HAO2, ACSL3, SCO2 CHRM1 1167/4885AKR1A1 381/4885CHRM3 1823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.