Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13922750 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1HPGDHTTCSNK2A1 | |
| SCHEMBL10184215 | 0.81 | FTO (0.50) | SMN1; SMN2ALDH1A1HPGDHTTCSNK2A1 | |
| SCHEMBL11070846 | 0.80 | LMNA (0.53) | LMNAADRA2BRAB9ACYP1A2L3MBTL1 | |
| SCHEMBL855667 | 0.80 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1HPGDHTTMAPT | |
| SCHEMBL51622 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1HPGDHTTMAPT | |
| SCHEMBL19145242 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1HPGDHTTCSNK2A1 | |
| SCHEMBL1004649 | 0.78 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1HPGDHTTMAPT | |
| SCHEMBL19459308 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1HPGDHTTCSNK2A1 | |
| SCHEMBL5013530 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1HPGDHTTCSNK2A1 | |
| SCHEMBL4579781 | 0.78 | MAPT (0.51) | SMN1; SMN2ALDH1A1HPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2023-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | MAPT, PSEN1, PSEN2 | SMN1; SMN2 67/4885ALDH1A1 4081/4885HPGD 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.