Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658350 | 0.89 | MAPT (0.45) | KDM4EALDH1A1RHEBRAB9ALMNA | |
| SCHEMBL2834492 | 0.88 | KDM4E (0.56) | KDM4EALDH1A1RHEBRAB9ALMNA | |
| SCHEMBL733150 | 0.88 | GABRG2 (0.44) | KDM4EALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL1505455 | 0.83 | GABRG2 (0.50) | ALDH1A1RAB9ANPC1HPGDCA12 | |
| SCHEMBL2516837 | 0.82 | DHODH (0.46) | KDM4EALDH1A1EGFR | |
| SCHEMBL731048 | 0.78 | BRD4 (0.43) | KDM4EALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL3655959 | 0.77 | ADORA3 (0.42) | KDM4EALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL7824396 | 0.77 | ALDH1A1 (0.39) | KDM4EALDH1A1LMNANFKB1NFKB2 | |
| SCHEMBL3659131 | 0.76 | HPGDS (0.39) | KDM4EALDH1A1RAB9APOLBMAPT | |
| SCHEMBL16749655 | 0.76 | CA1 (0.58) | KDM4EALDH1A1LMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034952-B2 | Supramolecular assemblies and building blocks | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-10-11 | — | — | US | disclosed |
| US-20090143596-A1 | Supramolecular Assemblies and Building Blocks | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143596-A1 | Supramolecular Assemblies and Building Blocks | TERB1, TBCB, PARG | KDM4E 3595/4885ALDH1A1 4780/4885RHEB 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.