SCHEMBL25137403

SCHEMBL25137403

CC(C)=C1N(C)c2ccc(C)cc2N1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.38
CNR1 P21554 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
NOTUM Q6P988 1/20 0.36
POLB P06746 2/20 0.33
LMNA P02545 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TRPA1 O75762 1/20 0.33
TERT O14746 1/20 0.33
HSD17B3 P37058 1/20 0.33
ALDH1A1 P00352 4/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17339860 0.82 TERT (0.41) HTTKMT2AKDM4EMEN1MAPT
SCHEMBL4624622 0.82 TERT (0.41) HTTKMT2AKDM4EMEN1MAPT
SCHEMBL25137415 0.77 MEN1 (0.43) HTTKMT2AKDM4EMEN1MAPT
SCHEMBL25137384 0.76 HTT (0.42) HTTKMT2AKDM4EMEN1MAPT
SCHEMBL12901940 0.76 MAOA (0.43) KMT2AMEN1MAPTLMNANPC1
SCHEMBL24186612 0.75 ALDH1A1 (0.39) KMT2AMEN1MAPTPKMLMNA
SCHEMBL10274619 0.69 HSD17B10 (0.48) KMT2APKMCNR1GPR55NPSR1
SCHEMBL10170807 0.68 ACHE (0.46) KMT2AKDM4EMEN1MAPTLMNA
SCHEMBL7263176 0.68 PSMB5 (0.42) KMT2AKDM4EMEN1MAPTNPSR1
SCHEMBL7270780 0.68 TSHR (0.46) KMT2AKDM4EMEN1MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP HTT 2222/4885KMT2A 4312/4885KDM4E 4314/4885
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP HTT 2222/4885KMT2A 4312/4885KDM4E 4314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.