Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 13/20 | 0.63 |
| ▸ | YAP1 | P46937 | 1/20 | 0.60 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.60 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etofenamate SCHEMBL25152 | 0.84 | LMNA (1.00) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL13318493 | 0.83 | LMNA (0.61) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL1774875 | 0.83 | RXFP1 (0.70) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL12606017 | 0.81 | RXFP1 (0.67) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL13299189 | 0.81 | SMN1; SMN2 (0.51) | LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13754010 | 0.81 | RXFP1 (0.73) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| Etofenamate SCHEMBL6836167 | 0.81 | LMNA (0.92) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL14192649 | 0.80 | RXFP1 (0.66) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL13929951 | 0.80 | RXFP1 (0.64) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL9268782 | 0.79 | RXFP1 (0.78) | LMNACYP1A2CYP2C9CYP2C19RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8278357-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-10-02 | — | — | US | disclosed |
| US-8278357-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-10-02 | — | — | US | disclosed |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-12 | — | — | US | disclosed |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-12 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| US-20100056591-A1 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-03-04 | — | — | US | disclosed |
| US-20100056591-A1 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-03-04 | — | — | US | disclosed |
| US-7632866-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY (IL) | 2009-12-15 | — | — | US | disclosed |
| US-7632866-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY (IL) | 2009-12-15 | — | — | US | disclosed |
| WO-2009037707-A2 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | LMNA 2393/4885CYP1A2 3315/4885CYP2C9 4025/4885 |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | LMNA 2393/4885CYP1A2 3315/4885CYP2C9 4025/4885 |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | KCNN2, KCNN1, KCNN3 | LMNA 1851/4885CYP1A2 2397/4885CYP2C9 2597/4885 |
| US-20100056591-A1 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | KCNN2, KCNN1, KCNN3 | LMNA 1851/4885CYP1A2 2397/4885CYP2C9 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.