Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491556 | 0.88 | ALDH1A1 (0.71) | ALDH1A1KMT2AL3MBTL1APPGAA | |
| SCHEMBL30659698 | 0.88 | ALDH1A1 (0.71) | ALDH1A1KMT2AL3MBTL1APPGAA | |
| SCHEMBL31648307 | 0.88 | ALDH1A1 (0.71) | ALDH1A1KMT2AL3MBTL1APPGAA | |
| Ammonia Solution, Strong SCHEMBL28264184 | 0.86 | ALDH1A1 (0.69) | ALDH1A1KMT2AL3MBTL1APPGAA | |
| SCHEMBL27893145 | 0.86 | ALDH1A1 (0.69) | ALDH1A1KMT2AL3MBTL1APPGAA | |
| SCHEMBL27673236 | 0.86 | ALDH1A1 (0.69) | ALDH1A1KMT2AL3MBTL1APPGAA | |
| SCHEMBL14937316 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KMT2AL3MBTL1APPGAA | |
| SCHEMBL10603067 | 0.85 | ALDH1A1 (0.67) | ALDH1A1KMT2AL3MBTL1APPGAA | |
| SCHEMBL10727818 | 0.85 | ALDH1A1 (0.67) | ALDH1A1KMT2AL3MBTL1APPGAA | |
| SCHEMBL23881959 | 0.83 | ALDH1A1 (0.65) | ALDH1A1KMT2AL3MBTL1APPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106191081-B | Molecular marker method for detecting anti-imazethapyr-imidazole genes of millet | 河北省农林科学院谷子研究所 | 2020-12-08 | — | — | CN | claimed |
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | SANOFI (FR) | 2023-07-13 | — | — | US | disclosed |
| CN-112236421-A | Pyrazole derivative and pest control agent | 组合化学工业株式会社 | 2021-01-15 | — | — | CN | disclosed |
| CN-112118830-A | High active agent loading solid dosage forms | 比利时胶囊公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-110996913-A | Novel oral formulation of belinostat | 欧恩科斯欧公司 | 2020-04-10 | — | — | CN | disclosed |
| US-10543227-B2 | Hair growth composition | RIKEN (JP) | 2020-01-28 | — | — | US | disclosed |
| CN-109796397-A | A kind of preparation method of 3- acetylpyridine | 浙江理工大学 | 2019-05-24 | — | — | CN | disclosed |
| US-20190015447-A1 | HAIR GROWTH COMPOSITION | RIKEN (JP) | 2019-01-17 | — | — | US | disclosed |
| CN-102307839-B | Method for producing aldehydes and ketones from primary and secondary alcohols | EVONIK DEGUSSA GMBH | 2015-03-11 | — | — | CN | disclosed |
| US-20110251399-A1 | METHOD FOR PRODUCING ALDEHYDES AND KETONES FROM PRIMARY AND SECONDARY ALCOHOLS | EVONIK DEGUSSA GMBH (DE) | 2011-10-13 | — | — | US | disclosed |
| US-6358976-B1 | FOR THERAPY AND PROPHYLAXIS OF CANCER METASTASIS, DIABETIC RETINOPATHY, NEOVASCULAR GLAUCOMA, THROMBOSIS, RESTENOSIS, OSTEOPOROSIS, OR MACULAR DEGENERATION | LANTHEUS MI REAL ESTATE, LLC | 2002-03-19 | — | — | US | disclosed |
| US-6130231-A | SUBSTITUTED 2,3-DIHYDROQUINOLIN-4-ONES | DUPONT PHARMACEUTICALS (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0944619-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5935966-A | COMPOUNDS THAT BLOCK THE ACTIVATION OF TRANSCRIPTION FACTORS THROUGH INHIBITION OF A FAMILY OF SPECIFIC KINASES, DECREASING PROINFLAMMATORY PROTEINS TO TREAT AUTOIMMUNE DISEASES AND AS GENERAL ANTIINFLAMMATORY AGENTS | SIGNAL PHARMACEUTICALS, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1998038171-A1 | PYRIMIDINE CARBOXYLATES AND RELATED COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS | SIGNAL PHARMACEUTICALS, INC. (US) | 1998-09-03 | — | — | WO | disclosed |
| WO-1998023608-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |
| WO-1997009325-A1 | PYRIMIDINE CARBOXYLATES AND RELATED COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS | SIGNAL PHARMACEUTICALS, INC. (US) | 1997-03-13 | — | — | WO | disclosed |
| CN-1105665-A | 5-{(imidazo{4,5-b}pyridin-3-yl)methyl}benzofuran derivatives | GLAXO GROUP LTD (GB) | 1995-07-26 | — | — | CN | disclosed |
| US-4723017-A | Process for preparing 3-hydroxy-3-(2-methyl-5-pyridyl)-propionic acid alkyl esters | LONZA LTD. (CH) | 1988-02-02 | — | — | US | disclosed |
| US-4687856-A | 3-hydroxy-3-(2-methyl-5-pyridyl)-propionic acid alkyl esters | LONZA LTD. (CH) | 1987-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251399-A1 | METHOD FOR PRODUCING ALDEHYDES AND KETONES FROM PRIMARY AND SECONDARY ALCOHOLS | ADH1A, ADH5, ADH1C | ALDH1A1 29/4885KMT2A 680/4885L3MBTL1 2904/4885 |
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | RIPK1, RIPK4, RIPK2 | ALDH1A1 2211/4885KMT2A 3609/4885L3MBTL1 4764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.