SCHEMBL25198302

SCHEMBL25198302

CN(C)[C](N(C)C)n1nnc2cc(Cl)ccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 3/20 0.51
CHEK1 O14757 1/20 0.43
LIMK1 P53667 1/20 0.43
MAPK14 Q16539 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
GLA P06280 1/20 0.43
THRB P10828 1/20 0.43
F12 P00748 1/20 0.40
MGAM O43451 3/20 0.40
AMY1A P0DUB6 3/20 0.40
GAA P10253 3/20 0.40
SI P14410 3/20 0.40
MGAM2 Q2M2H8 3/20 0.40
KMO O15229 1/20 0.38
KMT2A Q03164 5/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 2/20 0.37
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10428731 0.77 KCNMA1 (0.61) KCNMA1CHEK1LIMK1MAPK14CLK4
SCHEMBL10428898 0.77 KCNMA1 (0.61) KCNMA1CHEK1LIMK1MAPK14CLK4
SCHEMBL5654391 0.75 KCNMA1 (0.52) KCNMA1CHEK1LIMK1MAPK14CLK4
SCHEMBL427465 0.75 KCNMA1 (0.55) KCNMA1GLATHRBF12MGAM
SCHEMBL12053230 0.73 KCNMA1 (0.47) KCNMA1CHEK1LIMK1MAPK14CLK4
SCHEMBL26674481 0.72 KCNMA1 (0.41) KCNMA1CHEK1LIMK1MAPK14CLK4
SCHEMBL3278710 0.72 PKM (0.56) KCNMA1CHEK1LIMK1MAPK14CLK4
SCHEMBL3676899 0.72 PKM (0.56) KCNMA1CHEK1LIMK1MAPK14CLK4
SCHEMBL1133392 0.72 RAB9A (0.56) KCNMA1CHEK1LIMK1MAPK14CLK4
SCHEMBL11264259 0.71 CHEK1 (0.53) KCNMA1CHEK1LIMK1MAPK14CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023082084-A1 GEL MATERIAL, PREPARATION METHOD THEREFOR, AND USE THEREOF 爱美客技术发展股份有限公司 2023-05-19 WO disclosed