SCHEMBL252125

SCHEMBL252125

C=CCc1[c]c2ccccc2cc1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4671251 0.81 HPRT1 (0.41)
SCHEMBL21617926 0.79 GABRA1 (0.34) GABRA1GABRB2
SCHEMBL1560784 0.78
SCHEMBL11863358 0.77 CYP2A6 (0.32)
SCHEMBL4536755 0.76 GABRA1 (0.41) GABRA1GABRB2
SCHEMBL9466571 0.74 TRPA1 (0.32)
SCHEMBL6674217 0.74 TRPA1 (0.32)
SCHEMBL66086 0.74 CYP1A2 (0.39)
SCHEMBL6897074 0.74 LOXL2 (0.37)
SCHEMBL4271458 0.74 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 800 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113490769-B Rust preventive oil composition and method for producing same 出光兴产株式会社 2024-07-05 CN claimed
US-20240124419-A1 SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-04-18 US claimed
EP-4288416-A2 SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF The Regents Of The University Of Michigan (US) 2023-12-13 EP claimed
WO-2023141364-A1 SILYL-LIPID N-ACYL L-HOMOSERINE LACTONES AS QUORUM SENSING MOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-27 WO claimed
EP-3885425-B1 GREASE COMPOSITION FOR TAPERED ROLLER BEARING KYODO YUSHI (JP) 2023-06-28 EP claimed
CN-116217505-A Novel marker targeting agents for diagnosis or treatment of cancers expressing prostate specific membrane antigen 南京医科大学 2023-06-06 CN claimed
CN-112088191-B Composition, method for producing conductive film, and capacitor 出光兴产株式会社 2023-03-24 CN claimed
US-20230023289-A1 ANTHRANILAMIDE COMPOSITION FMC IP TECHNOLOGY GMBH (CH) 2023-01-26 US claimed
EP-3377104-B1 MODULATING PERMEABILITY OF THE BLOOD CEREBROSPINAL FLUID BARRIER MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-12-21 EP claimed
WO-2022169834-A2 SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-08-11 WO claimed
US-4920228-A N,N-disubstituted, α-(3,5-dialkyl-4-hydroxyphenyl)-α,α-disubstituted acetamides and composition stabilized therewith THE B. F. GOODRICH COMPANY (US) 1990-04-24 US claimed
US-4871753-A 3-Phenyl-5-trifluoromethyl-1,2,4-oxadiazole compounds which are useful pesticides CIBA-GEIGY CORPORATION (US) 1989-10-03 US claimed
US-4841053-A Process for desensitizing a 1-(alkylamino)alkyl-polysubstituted piperazinone during recovery THE B. F. GOODRICH COMPANY (US) 1989-06-20 US claimed
US-4808505-A Photosensitive member with enamine charge transport material MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-02-28 US claimed
US-4778612-A WEAR RESISTANCE; EXTREME PRESSURE LUBRICANTS CIBA-GEIGY CORPORATION (US) 1988-10-18 US claimed
US-4714705-A 4-nitrogen substituted isoquinolinol compounds having cardiotonic, phosphodiesterase fraction III inhibiting properties and/or renal vasodilating properties ORTHO PHARMACEUTICAL CORPORATION (US) 1987-12-22 US claimed
US-4130496-A ION EXCHANGE RESIN CATALYST MOBIL OIL CORPORATION (US) 1978-12-19 US claimed
US-4119558-A PHENYL, NAPHTHYL DIESTERS OF CHLOROBENZENE DICARBOXYLIC ACID THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1978-10-10 US claimed
US-4092254-A IMPROVED ANTIWEAR PROPERTIES MOBIL OIL CORPORATION (US) 1978-05-30 US claimed
US-3954845-A Synthetic detergents of the ampholytic betaine type, process for preparing the same and compositions MODOKEMI AKTIEBOLAG (SW) 1976-05-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124419-A1 SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF HSPA5, HSPA2, PSMG3 GABRA1 3031/4885GABRB2 2818/4885
US-20230023289-A1 ANTHRANILAMIDE COMPOSITION ACMSD, FADS2, AADAC GABRA1 2655/4885GABRB2 2182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.