Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5136127 | 0.88 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1ALDH1A1KDM4E | |
| SCHEMBL7477847 | 0.84 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1ALDH1A1KDM4E | |
| SCHEMBL6739223 | 0.84 | GABRA1 (0.38) | GABRA1GABRB2AKR1B1ALDH1A1KDM4E | |
| SCHEMBL3365612 | 0.84 | GABRA1 (0.38) | GABRA1GABRB2AKR1B1ALDH1A1KDM4E | |
| SCHEMBL14631768 | 0.80 | ALDH1A1 (0.40) | GABRA1GABRB2ALDH1A1KDM4EMEN1 | |
| SCHEMBL15756039 | 0.80 | GABRA1 (0.35) | GABRA1GABRB2AKR1B1 | |
| SCHEMBL21617926 | 0.77 | GABRA1 (0.34) | GABRA1GABRB2AKR1B1ALDH1A1KDM4E | |
| SCHEMBL3362979 | 0.77 | GABRA1 (0.33) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL20778 | 0.73 | — | — | |
| SCHEMBL252125 | 0.72 | GABRA1 (0.32) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 778 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659099-A | Alpha-carboxyl-beta-diimine nickel complex, preparation method and application thereof, and preparation method of ethylene-methyl acrylate copolymer | 中国石油天然气股份有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117015549-A | Preparation method of camptothecin derivative | 江苏恒瑞医药股份有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116134083-A | Flame retardant-stabilizer combinations for flame retardant polymers with improved hydrolytic stability and use thereof | 科莱恩国际有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-114105860-A | Catalytic asymmetric synthesis method and application of chiral oxindole spiro-analogue | 重庆大学 | 2022-03-01 | — | — | CN | claimed |
| CN-113582889-A | Sulfonylureas and related compounds and uses thereof | 昆士兰大学 | 2021-11-02 | — | — | CN | claimed |
| US-11130731-B2 | Sulfonylureas and related compounds and use of same | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2021-09-28 | — | — | US | claimed |
| CN-109563110-B | Quinolinyldiamido transition metal complexes, their production and use | 埃克森美孚化学专利公司 | 2021-08-20 | — | — | CN | claimed |
| CN-107428696-B | Sulfonylureas and related compounds and uses thereof | 昆士兰大学 | 2021-08-20 | — | — | CN | claimed |
| EP-3478694-B9 | QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2021-08-04 | — | — | EP | claimed |
| CN-109438518-B | Monosubstituted diazabenzimidazole carbene metal complexes for use in organic light emitting diodes | UDC 爱尔兰有限责任公司 | 2021-06-15 | — | — | CN | claimed |
| US-4407817-A | Fungicidal 3-(N-acyl-N-arylamino)- and 3-(N-thionoacyl-N-arylamino)-gamma-butyrolactones and gamma-thiobutyrolactones | CHEVRON RESEARCH COMPANY (US) | 1983-10-04 | — | — | US | claimed |
| US-4326077-A | HERBICIDE AND PLANT GROWTH REGULATOR | CHEVRON RESEARCH COMPANY (US) | 1982-04-20 | — | — | US | claimed |
| US-4318924-A | Combating bacteria with N-cycloalkyl-N'-substituted-N'-acyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | claimed |
| US-4311849-A | SULFIDING, ESTERIFICATION | CHEVRON RESEARCH (US) | 1982-01-19 | — | — | US | claimed |
| US-4260410-A | Herbicidal and plant-growth-regulating N-haloacetylphenylamino carbonyl oximes | CHEVRON RESEARCH COMPANY (US) | 1981-04-07 | — | — | US | claimed |
| US-4243408-A | PREEMERGENCE AND POSTEMERGENCE; SEEDICIDES | CHEVRON RESEARCH COMPANY (US) | 1981-01-06 | — | — | US | claimed |
| US-4174210-A | Herbicidal and plant-growth regulating N-haloacetylphenylamino carbonyl oximes | CHEVRON RESEARCH COMPANY (US) | 1979-11-13 | — | — | US | claimed |
| US-4107323-A | Fungicidal 3-(N-acyl-N-arylamino) lactones and lactams | CHEVRON RESEARCH COMPANY (US) | 1978-08-15 | — | — | US | claimed |
| US-4012519-A | Fungicidal 3-(N-acyl-N-arylamino) lactones and lactams | CHEVRON RESEARCH COMPANY (US) | 1977-03-15 | — | — | US | claimed |
| US-3933860-A | FUNGICIDES | CHEVRON RESEARCH COMPANY (US) | 1976-01-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130731-B2 | Sulfonylureas and related compounds and use of same | NLRP3, PYCARD, IAPP | GABRA1 2431/4885GABRB2 1251/4885AKR1B1 3207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.