Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252157 | 0.88 | GABRA1 (0.45) | GABRA1GABRB2AKR1B1KDM4EMEN1 | |
| SCHEMBL15756039 | 0.86 | GABRA1 (0.35) | GABRA1GABRB2AKR1B1 | |
| SCHEMBL7477847 | 0.78 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1KDM4EMEN1 | |
| SCHEMBL6739223 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2AKR1B1KDM4EMEN1 | |
| SCHEMBL3365612 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2AKR1B1KDM4EMEN1 | |
| SCHEMBL14631768 | 0.74 | ALDH1A1 (0.40) | GABRA1GABRB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL21617926 | 0.71 | GABRA1 (0.34) | GABRA1GABRB2AKR1B1KDM4EMEN1 | |
| SCHEMBL3362979 | 0.71 | GABRA1 (0.33) | GABRA1GABRB2KDM4EALDH1A1MAPT | |
| SCHEMBL20778 | 0.68 | — | — | |
| SCHEMBL252125 | 0.67 | GABRA1 (0.32) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392633-B1 | CONTINUOUS HYDROFORMYLATION PROCESS | DSM IP ASSETS BV (NL) | 2008-03-26 | — | — | EP | disclosed |
| US-7102033-B2 | Hydroformylation of olefins with carbon monoxide and hydrogen in the presence of a rhodium-organobisphosphite complex catalyst at a partial pressure of carbon monoxide and H2; conjugated alkadiene poisoning of the catalyst is reversed by an activating pressure of hydrogen or of carbon monoxide | DSM IP ASSETS B.V. (NL) | 2006-09-05 | — | — | US | disclosed |
| US-7087797-B2 | Continuous hydroformylation process | DSM IP ASSETS B.V. (NL) | 2006-08-08 | — | — | US | disclosed |
| EP-1383718-B1 | CONTINUOUS HYDROFORMYLATION PROCESS | DSM IP ASSETS BV (NL) | 2006-06-28 | — | — | EP | disclosed |
| US-20060052644-A1 | Hydroformylation of olefins with carbon monoxide and hydrogen in the presence of a rhodium-organobisphosphite complex catalyst at a partial pressure of carbon monoxide and H2; conjugated alkadiene poisoning of the catalyst is reversed by an activating pressure of hydrogen or of carbon monoxide | DSM I.P. ASSETS B.V. (NL) | 2006-03-09 | — | — | US | disclosed |
| US-20040152924-A1 | Continuous hydroformylation process | DSM I.P. ASSETS B.V. (NL) | 2004-08-05 | — | — | US | disclosed |
| US-20040143140-A1 | Continuous process for producing an aldehyde | DSM IP ASSETS B.V. (NL) | 2004-07-22 | — | — | US | disclosed |
| US-20040138508-A1 | Rapid, low temperature vacuum evaporator recovery of rhodium bisphosphite catalyst from high boiling point aldehydes without degradation | DSM I.P. ASSETS B.V. (NL) | 2004-07-15 | — | — | US | disclosed |
| EP-1392633-A1 | CONTINUOUS HYDROFORMYLATION PROCESS | DSM IP Assets B.V. (NL) | 2004-03-03 | — | — | EP | disclosed |
| EP-1383717-A1 | CONTINUOUS HYDROFORMYLATION PROCESS FOR PRODUCING AN ALDEHYDE | DSM IP Assets B.V. (NL) | 2004-01-28 | — | — | EP | disclosed |
| EP-1383728-A1 | CONTINUOUS PROCESS FOR PRODUCING AN ALDEHYDE | DSM IP Assets B.V. (NL) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002083617-A1 | CONTINUOUS PROCESS FOR PRODUCING AN ALDEHYDE | DSM IP ASSETS B.V. (NL) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002083613-A1 | CONTINUOUS HYDROFORMYLATION PROCESS | DSM IP ASSETS B.V. (NL) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002083604-A1 | CONTINUOUS HYDROFORMYLATION PROCESS FOR PRODUCING AN ALDEHYDE | DSM IP ASSETS B.V. (NL) | 2002-10-24 | — | — | WO | disclosed |
| EP-1249438-A1 | Continuous hydroformylation process for producing an aldehyde | DSM N.V. (NL) | 2002-10-16 | — | — | EP | disclosed |
| EP-1249445-A1 | Continuous process for producing an aldehyde | DSM N.V. (NL) | 2002-10-16 | — | — | EP | disclosed |
| EP-1249439-A1 | Continuous hydroformylation process | DSM N.V. (NL) | 2002-10-16 | — | — | EP | disclosed |
| EP-1249444-A1 | Continuous hydroformylation process for forming an aldehyde | DSM N.V. (NL) | 2002-10-16 | — | — | EP | disclosed |
| EP-1249441-A1 | Continuous hydroformylation process | DSM N.V. (NL) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138508-A1 | Rapid, low temperature vacuum evaporator recovery of rhodium bisphosphite catalyst from high boiling point aldehydes without degradation | VAPB, VAPA, MVD | GABRA1 3194/4885GABRB2 2949/4885AKR1B1 1676/4885 |
| US-20040143140-A1 | Continuous process for producing an aldehyde | ADH5, ADH1C, ADH1A | GABRA1 873/4885GABRB2 433/4885AKR1B1 480/4885 |
| US-20040152924-A1 | Continuous hydroformylation process | NUDT1, HMOX1, HRH4 | GABRA1 2971/4885GABRB2 2614/4885AKR1B1 1600/4885 |
| US-20060052644-A1 | Hydroformylation of olefins with carbon monoxide and hydrogen in the presence of a rhodium-organobisphosphite complex catalyst at a partial pressure of carbon monoxide and H2; conjugated alkadiene poisoning of the catalyst is reversed by an activating pressure of hydrogen or of carbon monoxide | HRH3, HRH1, HMOX2 | GABRA1 4078/4885GABRB2 3950/4885AKR1B1 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.