Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25246970 | 0.85 | BACE1 (0.33) | KLKB1BACE1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL18656545 | 0.80 | CSNK2A1 (0.46) | KLKB1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL8141320 | 0.80 | HRH3 (0.40) | KLKB1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL25240608 | 0.79 | LOXL2 (0.40) | CSNK2A2CSNK2BCSNK2A1CSNK2A3GAA | |
| SCHEMBL3074890 | 0.79 | GABRA1 (0.43) | — | |
| SCHEMBL25236316 | 0.77 | KDM4E (0.46) | GAATAAR1CYP1A2 | |
| SCHEMBL4518498 | 0.77 | ALDH1A1 (0.46) | GAATAAR1CYP1A2 | |
| SCHEMBL1758623 | 0.76 | PYCR1 (0.44) | GAATAAR1 | |
| SCHEMBL27263781 | 0.75 | SHBG (0.42) | KLKB1CSNK2A1HRH3 | |
| SCHEMBL23241569 | 0.73 | RXRA (0.49) | KLKB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118354781-A | Peptide inhibitors of interleukin-23 receptor | 西兰制药公司 | 2024-07-16 | — | — | CN | claimed |
| WO-2023099669-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR | ZEALAND PHARMA A/S (DK) | 2023-06-08 | — | — | WO | claimed |
| CN-118354781-A | Peptide inhibitors of interleukin-23 receptor | 西兰制药公司 | 2024-07-16 | — | — | CN | disclosed |
| WO-2023099669-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR | ZEALAND PHARMA A/S (DK) | 2023-06-08 | — | — | WO | disclosed |