SCHEMBL252362

SCHEMBL252362

CCN1CCCN2CCCN=C12

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
TSHR P16473 2/20 0.38
LMNA P02545 1/20 0.38
INMT O95050 3/20 0.35
USP2 O75604 1/20 0.35
CYP2D6 P10635 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
KDM2B Q8NHM5 5/20 0.33
CYP1A2 P05177 1/20 0.33
HTT P42858 2/20 0.32
ALDH1A1 P00352 1/20 0.31
TOP2A P11388 1/20 0.30
TOP2B Q02880 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251940 0.85 CYP2D6 (0.42) POLBTSHRLMNAINMTUSP2
SCHEMBL23571886 0.83 INMT (0.38) POLBTSHRLMNAINMTUSP2
SCHEMBL252415 0.82 CYP2D6 (0.44) POLBTSHRLMNAINMTUSP2
SCHEMBL8368647 0.80 ALDH1A1 (0.45) POLBTSHRLMNACYP2D6CYP3A4
SCHEMBL14572911 0.80 USP2 (0.35) INMTUSP2
SCHEMBL22106057 0.80 USP2 (0.35) TSHRINMTUSP2CYP2D6CYP3A4
SCHEMBL23075888 0.80 USP2 (0.35) TSHRINMTUSP2CYP2D6CYP3A4
SCHEMBL23075885 0.80 USP2 (0.35) INMTUSP2
SCHEMBL20686781 0.79 NCF1 (0.34) POLBINMTUSP2
SCHEMBL9984629 0.79 CYP2D6 (0.41) POLBTSHRLMNAINMTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10640641-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2020-05-05 US claimed
US-20200062953-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2020-02-27 US claimed
US-10556917-B1 Method for preparing bis-(silylalkyl)carbonate esters UCHICAGO ARGONNE, LLC (US) 2020-02-11 US claimed
WO-2019157357-A1 PROCESSES FOR PREPARING CALIXARENES SI GROUP, INC. (US) 2019-08-15 WO claimed
US-20190248721-A1 PROCESSES FOR PREPARING CALIXARENES SI GROUP, INC. 2019-08-15 US claimed
US-10336863-B2 Curable composition having a special catalyst/softner system HENKEL AG & CO. KGAA (DE) 2019-07-02 US claimed
US-20180237635-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2018-08-23 US claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
US-9944593-B2 Process for the synthesis of fluoralkyl sulfonate salts SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2018-04-17 US claimed
EP-1930376-B2 CURABLE COMPOSITION KANEKA CORP (JP) 2016-09-07 EP claimed
WO-2016137881-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES (US) 2016-09-01 WO claimed
US-20160244606-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2016-08-25 US claimed
WO-2012036392-A3 HUMAN ANTI-EPIDERMAL GROWTH FACTOR RECEPTOR FAB ANTIBODY AND A PHARMACEUTICAL COMPOSITION FOR TREATING TUMOURS COMPRISING THE SAME 주식회사 아이지세라피 (KR) 2012-05-10 WO claimed
EP-1930376-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2011-12-07 EP claimed
US-8013080-B2 Curable composition KANEKA CORPORATION (JP) 2011-09-06 US claimed
EP-4470792-B1 VOC-FREE COUPLING AGENTS FOR RUBBER COMPOSITIONS GOODYEAR TIRE & RUBBER (US) 2026-03-18 EP disclosed
EP-4692148-A1 CURABLE COMPOSITION AND CURED PRODUCT OF SAME DIC Corporation (JP) 2026-02-11 EP disclosed
EP-0626410-B1 Method for making polycarbonates GEN ELECTRIC (US) 1999-01-07 EP disclosed
EP-0626410-A2 Method for making polycarbonates GENERAL ELECTRIC COMPANY (US) 1994-11-30 EP disclosed
US-5319066-A Method for making polycarbonates GENERAL ELECTRIC COMPANY (US) 1994-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248721-A1 PROCESSES FOR PREPARING CALIXARENES CALU, CALD1, CALR POLB 1641/4885TSHR 4680/4885LMNA 2113/4885
US-10556917-B1 Method for preparing bis-(silylalkyl)carbonate esters RIOK1, SRM, SMS POLB 875/4885TSHR 1773/4885LMNA 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.