Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 5/20 | 0.55 |
| ▸ | GABRD | O14764 | 5/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.55 |
| ▸ | GABRE | P78334 | 5/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.55 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17917509 | 0.81 | KMT2A (0.54) | GPR35MEN1MAPTKMT2AGAA | |
| SCHEMBL8816924 | 0.77 | GABRA1 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15497548 | 0.77 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23436651 | 0.77 | GABRA1 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12396554 | 0.76 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2370924 | 0.75 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3385902 | 0.74 | MAOA (0.57) | GPR35MEN1MAPTKMT2AGAA | |
| SCHEMBL18862541 | 0.73 | GPR35 (0.47) | GPR35MEN1MAPTKMT2AGAA | |
| SCHEMBL25290758 | 0.73 | MAPT (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19346715 | 0.73 | TP53 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |