Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 10/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL29354256 | 1.00 | CLTC (0.42) | CLTCFTOMEN1POLBCCR6 | |
| Lithium Ion SCHEMBL94590 | 0.85 | CLTC (0.42) | CLTCFTOMEN1POLBCCR6 | |
| SCHEMBL16097930 | 0.83 | ALDH1A1 (0.33) | CLTC | |
| Potassium Ion SCHEMBL5415633 | 0.77 | CLTC (0.45) | CLTCFTOMEN1POLBCCR6 | |
| Potassium Ion SCHEMBL4636440 | 0.72 | CLTC (0.46) | CLTCFTOMEN1POLBCCR6 | |
| Potassium Ion SCHEMBL31670338 | 0.72 | CLTC (0.46) | CLTCFTOMEN1POLBCCR6 | |
| Lithium Ion SCHEMBL95351 | 0.69 | CLTC (0.44) | CLTCMEN1KMT2A | |
| Lithium Ion SCHEMBL29875131 | 0.69 | CLTC (0.44) | CLTCMEN1KMT2A | |
| SCHEMBL8032702 | 0.68 | ALDH1A1 (0.33) | CLTC | |
| SCHEMBL7705622 | 0.67 | ALDH1A1 (0.32) | CLTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458571-B1 | PROCESS FOR GENERATING RENAL TUBULES | LEIBNIZ INST POLYMERFORSCHUNG DRESDEN EV (DE) | 2023-07-05 | — | — | EP | disclosed |