Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 10/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.30 |
| ▸ | APEX1 | P27695 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL25250540 | 0.85 | CLTC (0.42) | CLTCFTOPOLBBLMKMT2A | |
| Lithium Ion SCHEMBL29354256 | 0.85 | CLTC (0.42) | CLTCFTOPOLBBLMKMT2A | |
| SCHEMBL8032702 | 0.84 | ALDH1A1 (0.33) | CLTCALDH1A1HSD17B10 | |
| SCHEMBL7705622 | 0.83 | ALDH1A1 (0.32) | CLTCALDH1A1HSD17B10 | |
| Lithium SCHEMBL4587867 | 0.83 | ALDH1A1 (0.32) | CLTCALDH1A1HSD17B10 | |
| Potassium Ion SCHEMBL5415633 | 0.76 | CLTC (0.45) | CLTCFTOPOLBBLMKMT2A | |
| SCHEMBL16316878 | 0.73 | L3MBTL1 (0.38) | POLBBLMKMT2AMEN1ALDH1A1 | |
| Potassium Ion SCHEMBL31670338 | 0.71 | CLTC (0.46) | CLTCFTOPOLBBLMKMT2A | |
| Potassium Ion SCHEMBL4636440 | 0.71 | CLTC (0.46) | CLTCFTOPOLBBLMKMT2A | |
| SCHEMBL16097930 | 0.68 | ALDH1A1 (0.33) | CLTCALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1568 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11906432-B2 | Enhanced, rapid, homogeneous, cell staining and assay | ESSENLIX CORPORATION (US) | 2024-02-20 | — | — | US | claimed |
| US-11371085-B2 | Reagents and methods for isothermal chain reaction | MANCEBO RICARDO (US) | 2022-06-28 | — | — | US | claimed |
| US-20210292353-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-09-23 | — | — | US | claimed |
| US-20210247317-A1 | ENHANCED, RAPID, HOMOGENEOUS, CELL STAINING AND ASSAY | ESSENLIX CORPORATION (US) | 2021-08-12 | — | — | US | claimed |
| EP-3841368-A1 | ENHANCED, RAPID, HOMOGENEOUS, CELL STAINING AND ASSAY | Essenlix Corporation (US) | 2021-06-30 | — | — | EP | claimed |
| EP-3829565-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | Karlsruher Institut für Technologie (DE) | 2021-06-09 | — | — | EP | claimed |
| US-20200400663-A1 | SILICA NANOPARTICLES FOR BIOMARKER DIAGNOSIS AND METHOD FOR PRODUCING SAME | DXGEN CORP. (KR) | 2020-12-24 | — | — | US | claimed |
| EP-3726215-A1 | SILICA NANOPARTICLES FOR BIOMARKER DIAGNOSIS AND METHOD FOR PRODUCING SAME | DxGen Corp. (KR) | 2020-10-21 | — | — | EP | claimed |
| EP-3174953-B1 | ENVIRONMENTALLY RESPONSIVE CHROMATIC LUMINESCENT COMPOSITIONS WITH IMPROVED HAND | BAMBU VAULT LLC (US) | 2020-09-02 | — | — | EP | claimed |
| US-20200239945-A1 | REAGENTS AND METHODS FOR ISOTHERMAL CHAIN REACTION | MANCEBO RICARDO (US) | 2020-07-30 | — | — | US | claimed |
| WO-2001036663-A9 | BIO-BURDEN VISUALIZATION SYSTEM | CHEMCLEAN CORP (US) | 2002-08-29 | — | — | WO | claimed |
| EP-1117986-A1 | METHOD FOR IMAGING TISSUE | Rogers Imaging Corporation (US) | 2001-07-25 | — | — | EP | claimed |
| WO-2001036663-A2 | BIO-BURDEN VISUALIZATION SYSTEM | CHEMCLEAN CORPORATION (US) | 2001-05-25 | — | — | WO | claimed |
| US-6232092-B1 | Method for preparing biological specimens for visual analysis | ROGERS IMAGING CORPORATION | 2001-05-15 | — | — | US | claimed |
| WO-2000020846-A9 | METHOD FOR IMAGING TISSUE | ROGERS IMAGING CORP (US) | 2001-03-22 | — | — | WO | claimed |
| WO-2000020846-A1 | METHOD FOR IMAGING TISSUE | ROGERS IMAGING CORPORATION (US) | 2000-04-13 | — | — | WO | claimed |
| EP-0595806-A1 | ANALYSIS OF CARBOHYDRATES AND KITS THEREFORE | ASTROSCAN LIMITED (GB) | 1994-05-11 | — | — | EP | claimed |
| WO-1993002356-A1 | ANALYSIS OF CARBOHYDRATES AND KITS THEREFORE | ASTROSCAN, LTD. (GB) | 1993-02-04 | — | — | WO | claimed |
| WO-1991018912-A1 | DERIVATIZATION AND IDENTIFICATION OF SACCHARIDES | UNIV TEXAS (US) | 1991-12-12 | — | — | WO | claimed |
| EP-0279757-A1 | Kit for use as an agent for the selective destruction of transformed cells | CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER DE L'ORGANISATION MONDIALEDE LA SANTE (FR) | 1988-08-24 | — | — | EP | claimed |