SCHEMBL25253595

SCHEMBL25253595

CN(C)C(=O)c1cc(O)c(N)c([N+](=O)[O-])c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
HTT P42858 1/20 0.47
LMNA P02545 3/20 0.45
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
ERN1 O75460 2/20 0.44
TPMT P51580 1/20 0.43
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TTR P02766 4/20 0.41
COMT P21964 2/20 0.41
ABCC3 O15438 1/20 0.41
ABCC4 O15439 1/20 0.41
NR1I2 O75469 1/20 0.41
ABCB11 O95342 1/20 0.41
NR3C1 P04150 1/20 0.41
PGR P06401 1/20 0.41
HTR1A P08908 1/20 0.41
ADORA3 P0DMS8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29447926 1.00 KMT2A (0.47) KMT2AHTTLMNAALDH1A1L3MBTL1
SCHEMBL4632242 0.90 KMT2A (0.53) KMT2AHTTLMNAALDH1A1L3MBTL1
SCHEMBL4633313 0.86 KMT2A (0.49) KMT2AHTTLMNAALDH1A1L3MBTL1
SCHEMBL29809012 0.84 ALDH1A1 (0.51) KMT2AHTTLMNAALDH1A1L3MBTL1
SCHEMBL25298464 0.84 ALDH1A1 (0.51) KMT2AHTTLMNAALDH1A1L3MBTL1
SCHEMBL20839509 0.78 TPMT (0.54) KMT2ALMNAALDH1A1L3MBTL1ERN1
SCHEMBL29547015 0.78 ALDH1A1 (0.53) KMT2AHTTLMNAALDH1A1L3MBTL1
SCHEMBL25295791 0.77 MAPT (0.44) KMT2AHTTLMNAALDH1A1L3MBTL1
SCHEMBL22115119 0.76 LMNA (0.66) KMT2AHTTLMNAALDH1A1L3MBTL1
SCHEMBL11095256 0.73 GPR35 (0.62) KMT2ALMNAALDH1A1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051287-A1 METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES HK INNO.N CORPORATION (KR) 2025-02-13 US disclosed
CN-116354889-B Process for preparing benzimidazole derivatives 怡诺安有限公司 2025-01-14 CN disclosed
EP-4457216-A1 METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES HK inno.N Corporation (KR) 2024-11-06 EP disclosed
WO-2023128525-A1 METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES HK INNO.N CORPORATION (KR) 2023-07-06 WO disclosed
CN-116354889-A Process for preparing benzimidazole derivatives 怡诺安有限公司 2023-06-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051287-A1 METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES CYP3A4, CYP3A5, TMBIM6 KMT2A 1897/4885HTT 3576/4885LMNA 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.