Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25188259 | 1.00 | LMNA (0.44) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL24983856 | 0.82 | NFKB1 (0.43) | SLC6A2SLC6A3MAOBMAPTL3MBTL1 | |
| SCHEMBL25190606 | 0.81 | NFKB1 (0.42) | LMNACYP1A2CYP2C19MAOBGAA | |
| SCHEMBL25190608 | 0.81 | NFKB1 (0.42) | LMNACYP1A2CYP2C19MAOBGAA | |
| SCHEMBL8550039 | 0.81 | TNKS2 (0.47) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL3672681 | 0.80 | CA2 (0.50) | MAOBMAOARAB9ASMN1; SMN2CA2 | |
| SCHEMBL30315348 | 0.79 | NFKB1 (0.38) | CYP2C19MAOBMAPT | |
| SCHEMBL17227883 | 0.79 | NFKB1 (0.38) | CYP2C19MAOBMAPT | |
| SCHEMBL10653876 | 0.79 | NFKB1 (0.53) | PTGS2MAOBMAOAMAPTRAB9A | |
| SCHEMBL25187435 | 0.79 | NFKB1 (0.53) | PTGS2MAOBMAOAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952358-B2 | Flavan-3-ol analogs and anti-inflammatory activity | HONG KONG BAPTIST UNIVERSITY (CN) | 2024-04-09 | — | — | US | disclosed |
| US-20230159482-A1 | FLAVAN-3-OL ANALOGS AND ANTI-INFLAMMATORY ACTIVITY | HONG KONG BAPTIST UNIVERSITY (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952358-B2 | Flavan-3-ol analogs and anti-inflammatory activity | IL1A, IL6, IL1B | LMNA 1569/4885CYP1A2 904/4885PTGS1 20/4885 |
| US-20230159482-A1 | FLAVAN-3-OL ANALOGS AND ANTI-INFLAMMATORY ACTIVITY | IL1A, IL6, IL1B | LMNA 1569/4885CYP1A2 904/4885PTGS1 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.