Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.45 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | DDO | Q99489 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25267 | 0.81 | MTNR1A (0.62) | MTNR1AMTNR1BRHEBKMT2ANR3C1 | |
| SCHEMBL19447299 | 0.79 | MTNR1A (0.44) | MTNR1AMTNR1BRHEBPARP1KMT2A | |
| SCHEMBL24451623 | 0.77 | MTNR1A (0.45) | MTNR1AMTNR1BRHEBPARP1KMT2A | |
| SCHEMBL9539022 | 0.76 | ALDH1A1 (0.49) | MTNR1AMTNR1BRHEBLMNAKMT2A | |
| SCHEMBL24451734 | 0.76 | HTR1A (0.37) | MTNR1AMTNR1BRHEBLMNAENPP2 | |
| SCHEMBL24380298 | 0.75 | PARP1 (0.39) | MTNR1AMTNR1BPARP1KIF11DAO | |
| SCHEMBL5768529 | 0.74 | SRD5A2 (0.61) | MTNR1AMTNR1BRHEB | |
| SCHEMBL20125059 | 0.72 | DAO (0.60) | MTNR1AMTNR1BPARP1KMT2ANR3C1 | |
| Acetic Acid SCHEMBL11383873 | 0.71 | MTNR1A (0.45) | MTNR1AMTNR1BRHEBKMT2AMEN1 | |
| SCHEMBL7993891 | 0.71 | MTNR1A (0.54) | MTNR1AMTNR1BRHEBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352363-B1 | Spiropyrrolidine derived antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2022-06-07 | — | — | US | disclosed |
| WO-2022109363-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352363-B1 | Spiropyrrolidine derived antiviral agents | ACE, ACE2, REN | MTNR1A 4034/4885MTNR1B 4017/4885RHEB 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.