Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15968524 | 0.77 | MEN1 (0.40) | ALDH1A1POLBTHRBL3MBTL1KDM4E | |
| SCHEMBL28048827 | 0.76 | MPO (0.40) | ERN1KMT2AMEN1ELANE | |
| SCHEMBL11752400 | 0.75 | LMNA (0.41) | ALDH1A1LMNAPOLBADORA3KDM4E | |
| SCHEMBL5752394 | 0.74 | MPO (0.51) | ERN1LMNAKDM4E | |
| SCHEMBL1149953 | 0.73 | MPO (0.36) | ERN1ALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL4360026 | 0.73 | ALDH1A1 (0.41) | ERN1ALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL18096451 | 0.70 | PTGER4 (0.47) | ALDH1A1LMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL28456400 | 0.69 | MPO (0.42) | ALDH1A1L3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL28707953 | 0.69 | MPO (0.54) | ERN1ALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL5176409 | 0.69 | KMT2A (0.35) | ERN1ALDH1A1LMNAPOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | GSK3A, GSK3B, WNT1 | ERN1 3532/4885ALDH1A1 1093/4885LMNA 1507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.