Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CLPP | Q16740 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25200012 | 0.81 | PLA2G2A (0.44) | HRH3APPMCHR1ALDH1A1KDM4E | |
| SCHEMBL29348983 | 0.77 | AR (0.38) | ALDH1A1LMNANPC1L3MBTL1 | |
| SCHEMBL839553 | 0.76 | HDAC6 (0.45) | HSD11B1 | |
| SCHEMBL25275022 | 0.75 | LIPG (0.40) | HRH3PLA2G2ABTK | |
| SCHEMBL24665502 | 0.72 | P2RX7 (0.39) | BTK | |
| SCHEMBL24664735 | 0.70 | P2RX7 (0.41) | MCHR1PLA2G2ABTKPOLBNPC1 | |
| SCHEMBL23995201 | 0.70 | ALDH1A1 (0.50) | HRH3APPMCHR1ALDH1A1PLA2G2A | |
| SCHEMBL10841960 | 0.69 | APP (0.62) | HRH3APPMCHR1CLPPPOLB | |
| SCHEMBL6824717 | 0.69 | L3MBTL1 (0.65) | HRH3BTKPOLBL3MBTL1HSD11B1 | |
| SCHEMBL16891466 | 0.69 | L3MBTL1 (0.70) | HRH3ALDH1A1KDM4EBTKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097187-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023097187-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2023-06-01 | — | — | WO | disclosed |