Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 10/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30476358 | 0.85 | POLB (0.47) | KDM4EALDH1A1KMT2AMGLLPLA2G7 | |
| SCHEMBL20818190 | 0.85 | POLB (0.47) | KDM4EALDH1A1KMT2AMGLLPLA2G7 | |
| SCHEMBL25239622 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1KMT2AMEN1APP | |
| SCHEMBL20818138 | 0.81 | LMNA (0.43) | KDM4EALDH1A1MAPTL3MBTL1GAA | |
| SCHEMBL25232426 | 0.81 | MGLL (0.41) | KDM4EALDH1A1KMT2AMEN1MGLL | |
| SCHEMBL25233670 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1KMT2AMEN1MGLL | |
| SCHEMBL25232053 | 0.78 | APP (0.43) | KDM4EALDH1A1KMT2ATSHRAPP | |
| SCHEMBL20818072 | 0.77 | PTGDR2 (0.40) | — | |
| SCHEMBL25233763 | 0.76 | APP (0.44) | KDM4EALDH1A1KMT2ATSHRAPP | |
| SCHEMBL4754240 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | PDXK, ATP6V1B1, REN | KDM4E 3899/4885ALDH1A1 649/4885KMT2A 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.