Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301240 | 0.84 | USP30 (0.41) | MGLLLMNATP53MAPTCNR1 | |
| SCHEMBL25296236 | 0.81 | FASN (0.50) | MGLLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL25295004 | 0.80 | PTGDR2 (0.44) | MGLLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL23453444 | 0.77 | SMN1; SMN2 (0.49) | ALDH1A1PROKR1NPC1LMNATP53 | |
| SCHEMBL25944457 | 0.77 | HTR3A (0.41) | NPSR1ALDH1A1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL25259801 | 0.72 | PRKAB2 (0.42) | MGLLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL23211920 | 0.71 | SCD5 (0.41) | MGLLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL23150548 | 0.70 | CYP3A4 (0.48) | ALDH1A1CYP3A4CYP2C9APPNPC1 | |
| SCHEMBL2732137 | 0.69 | MGLL (0.44) | MGLLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL18585817 | 0.68 | HSD11B1 (0.53) | NPSR1ALDH1A1NPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981661-B2 | Heterocyclic compounds | HOFFMANN-LA ROCHE INC. (US) | 2024-05-14 | — | — | US | disclosed |
| EP-4208456-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2023-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11981661-B2 | Heterocyclic compounds | CBR3, BRIX1, CCNY | MGLL 996/4885NPSR1 2057/4885ALDH1A1 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.