Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 4/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25913446 | 0.69 | MAOA (0.35) | BRAFRAF1SCN7AKCNH2 | |
| SCHEMBL25913399 | 0.68 | CSF1R (0.39) | BRAFRAF1 | |
| SCHEMBL25914740 | 0.66 | CSF1R (0.35) | BRAFRAF1 | |
| SCHEMBL25911790 | 0.65 | CSF1R (0.53) | BRAFRAF1 | |
| SCHEMBL25914331 | 0.63 | DYRK1A (0.35) | BRAF | |
| SCHEMBL25314973 | 0.62 | BRAF (0.42) | BRAFRAF1 | |
| SCHEMBL25914665 | 0.62 | CSF1R (0.39) | BRAFRAF1 | |
| SCHEMBL25912751 | 0.62 | MAPK8 (0.39) | BRAF | |
| SCHEMBL30467033 | 0.61 | BRAF (0.35) | BRAF | |
| SCHEMBL25913001 | 0.61 | BRAF (0.35) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |