Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD5 | P21918 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723493 | 0.86 | DRD2 (0.54) | DRD3DRD2DRD5HTR7KDM4E | |
| SCHEMBL25323565 | 0.85 | DRD2 (0.49) | DRD3DRD2DRD5HTR7KDM4E | |
| SCHEMBL5661060 | 0.83 | HTR1A (0.53) | DRD3DRD2DRD5HTR7SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5658805 | 0.82 | KCNH2 (0.54) | DRD3DRD2DRD5HTR7SIGMAR1 | |
| SCHEMBL25330979 | 0.78 | NPC1 (0.57) | DRD3DRD2DRD5HTR7SIGMAR1 | |
| SCHEMBL30073106 | 0.77 | KDM4E (0.72) | DRD3DRD2DRD5HTR7KDM4E | |
| SCHEMBL30073110 | 0.77 | KDM4E (0.72) | DRD3DRD2DRD5HTR7KDM4E | |
| SCHEMBL25225949 | 0.77 | KDM4E (0.59) | DRD3DRD2DRD5HTR7KDM4E | |
| SCHEMBL5657962 | 0.75 | HTR1A (0.55) | DRD3DRD2DRD5HTR7 | |
| SCHEMBL741365 | 0.75 | ALOX15 (0.65) | DRD3DRD2DRD5HTR7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331672-A1 | 6-METHOXY-2-PHENETHYL ISOINDOLINE-1-ONE DERIVATIVE AND COMPOSITION FOR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME | CNG BIO CO., LTD. (KR) | 2023-10-19 | — | — | US | disclosed |
| US-20230331672-A1 | 6-METHOXY-2-PHENETHYL ISOINDOLINE-1-ONE DERIVATIVE AND COMPOSITION FOR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME | CNG BIO CO., LTD. (KR) | 2023-10-19 | — | — | US | disclosed |
| EP-4219450-A1 | 6-METHOXY-2-PHENETHYL ISOINDOLINE-1-ONE DERIVATIVE AND COMPOSITION FOR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME | CNG Bio Co., Ltd. (KR) | 2023-08-02 | — | — | EP | disclosed |
| EP-4219450-A1 | 6-METHOXY-2-PHENETHYL ISOINDOLINE-1-ONE DERIVATIVE AND COMPOSITION FOR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME | CNG Bio Co., Ltd. (KR) | 2023-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331672-A1 | 6-METHOXY-2-PHENETHYL ISOINDOLINE-1-ONE DERIVATIVE AND COMPOSITION FOR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME | NGF, BDNF, NTRK2 | DRD3 1123/4885DRD2 477/4885DRD5 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.