SCHEMBL25333486

SCHEMBL25333486

O=C1N=CN=C2C1=NC(=O)N2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 3/20 0.41
▸ MAPT P10636 2/20 0.41
▸ PYGM P11217 3/20 0.41
▸ LMNA P02545 3/20 0.39
▸ MTOR P42345 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ TP53 P04637 2/20 0.39
▸ THRB P10828 1/20 0.39
▸ MDM2 Q00987 1/20 0.39
▸ NCOA1 Q15788 1/20 0.39
▸ NCOA3 Q9Y6Q9 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ GMNN O75496 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ DNMT1 P26358 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27643139 0.88 CDA (0.40) CDAMAPTPYGMLMNAMTOR
SCHEMBL31685351 0.87 MEN1 (0.35) CDAMAPTTK2
SCHEMBL31685169 0.84 ADORA1 (0.39) —
SCHEMBL31685179 0.83 UMPS (0.45) —
SCHEMBL114650 0.79 LMNA (0.45) CDAMAPTPYGMLMNAMTOR
SCHEMBL31685741 0.76 LGALS8 (0.35) CDAMAPTTK2
Phosphoric Acid SCHEMBL20305093 0.75 LMNA (0.42) CDAMAPTPYGMLMNAMTOR
Phosphoric Acid SCHEMBL6465085 0.75 LMNA (0.42) CDAMAPTPYGMLMNAMTOR
SCHEMBL31685237 0.75 CDA (0.43) CDAMAPTPYGMTK2
SCHEMBL31685355 0.74 CDA (0.42) CDAMAPTPYGMLMNAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388886-A1 Cas12a Endonuclease Variants and Methods of Use ENSOMA APS (DK) 2025-12-25 — — US disclosed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed
EP-4460566-A2 CAS12A ENDONUCLEASE VARIANTS AND METHODS OF USE Ensoma ApS (DK) 2024-11-13 — — EP disclosed
CN-118742641-A CAS12A endonuclease variants and methods of use 安索玛私人有限责任公司 2024-10-01 — — CN disclosed
WO-2023131870-A2 ENDONUCLEASE VARIANTS AND METHODS OF USE TWELVE BIO APS (DK) 2023-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388886-A1 Cas12a Endonuclease Variants and Methods of Use CDA, MUS81, DNASE1L3 CDA 1/4885MAPT 2832/4885PYGM 872/4885
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 CDA 275/4885MAPT 953/4885PYGM 1652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback