SCHEMBL27643139

SCHEMBL27643139

N=C1N=CN=C2C1=NC(=O)N2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 3/20 0.40
▸ MAPT P10636 2/20 0.40
▸ PYGM P11217 3/20 0.40
▸ LMNA P02545 3/20 0.38
▸ MTOR P42345 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ TP53 P04637 2/20 0.38
▸ THRB P10828 1/20 0.38
▸ MDM2 Q00987 1/20 0.38
▸ NCOA1 Q15788 1/20 0.38
▸ NCOA3 Q9Y6Q9 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ GMNN O75496 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ DNMT1 P26358 1/20 0.38
▸ THPO P40225 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25333486 0.88 CDA (0.41) CDAMAPTPYGMLMNAMTOR
SCHEMBL31685741 0.87 LGALS8 (0.35) CDAMAPTTK2
SCHEMBL31685232 0.85 CYP2C19 (0.40) —
SCHEMBL31685543 0.84 UMPS (0.48) —
SCHEMBL31685351 0.76 MEN1 (0.35) CDAMAPTTK2
SCHEMBL31685169 0.73 ADORA1 (0.39) —
SCHEMBL31685237 0.73 CDA (0.43) CDAMAPTPYGMTK2
SCHEMBL31685179 0.73 UMPS (0.45) —
SCHEMBL114650 0.72 LMNA (0.45) CDAMAPTPYGMLMNAMTOR
SCHEMBL31685392 0.72 LMNA (0.43) CDAMAPTPYGMLMNAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630985-B1 SYNTHESIS AND STRUCTURE OF HIGH POTENCY RNA THERAPEUTICS ARCTURUS THERAPEUTICS INC (US) 2025-08-27 — — EP claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 — — US claimed
EP-4602052-A1 PROTEIN-BASED SIGNAL AMPLIFICATION California Institute of Technology (US) 2025-08-20 — — EP claimed
WO-2025128901-A1 CIRCULAR RNA MOLECULES ARCTURUS THERAPEUTICS, INC. (US) 2025-06-19 — — WO claimed
WO-2025122628-A1 CIRCULARIZED RNAS AND METHODS OF MAKING THE SAME HELIX NANOTECHNOLOGIES INC (US) 2025-06-12 — — WO claimed
EP-4558630-A1 METHODS AND APPARATUS FOR DUPLEX NUCLEOTIDE PURIFICATION Agilent Technologies, Inc. (US) 2025-05-28 — — EP claimed
WO-2025081087-A1 METHODS FOR CENTRAL NERVOUS SYSTEM NUCLEIC ACID DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2025-04-17 — — WO claimed
WO-2025081080-A1 COMPOSITIONS FOR CENTRAL NERVOUS SYSTEM NUCLEIC ACID DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2025-04-17 — — WO claimed
EP-3871696-B1 LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA TRANSLATE BIO INC (US) 2025-03-19 — — EP claimed
WO-2025024442-A1 COMPOSITIONS AND METHODS FOR TREATING CONDITIONS ASSOCIATED WITH BSEP DEFICIENCY ULTRAGENYX PHARMACEUTICAL INC. (US) 2025-01-30 — — WO claimed
WO-2023086893-A1 COMPOSITION AND METHODS FOR TREATMENT OF PRIMARY CILIARY DYSKINESIA TRANSLATE BIO, INC. (US) 2023-05-19 — — WO claimed
EP-4146680-A1 COMPOSITION AND METHODS FOR TREATMENT OF PRIMARY CILIARY DYSKINESIA Translate Bio, Inc. (US) 2023-03-15 — — EP claimed
WO-2023023528-A1 CELL-TO-CELL DELIVERY OF RNA CIRCUITS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-02-23 — — WO claimed
WO-2022204549-A1 OPTIMIZED NUCLEOTIDE SEQUENCES ENCODING THE EXTRACELLULAR DOMAIN OF HUMAN ACE2 PROTEIN OR A PORTION THEREOF TRANSLATE BIO, INC. (US) 2022-09-29 — — WO claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 — — WO claimed
EP-3587409-B1 BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS TRANSLATE BIO INC (US) 2022-06-01 — — EP claimed
EP-3976115-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF HEMOCHROMATOSIS Ultragenyx Pharmaceutical Inc. (US) 2022-04-06 — — EP claimed
CN-106795142-A Stereochemically enriched compositions for delivery of nucleic acids 夏尔人类遗传性治疗公司 2017-05-31 — — CN claimed
CN-105813656-A LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA 夏尔人类遗传性治疗公司 2016-07-27 — — CN claimed
CN-105658800-A CNS delivery of MRNA and uses thereof 夏尔人类遗传性治疗公司 2016-06-08 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT CDA 794/4885MAPT 1540/4885PYGM 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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