Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.45 |
| ▸ | CSF1R | P07333 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | BRAF | P15056 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544034 | 1.00 | TRPV1 (0.45) | TRPV1CSF1RKDRBRAFMAPK14 | |
| SCHEMBL25340961 | 0.86 | TRPV1 (0.45) | TRPV1CSF1RKDRBRAFMAPK14 | |
| SCHEMBL25339233 | 0.85 | TRPV1 (0.39) | TRPV1CSF1R | |
| SCHEMBL25338732 | 0.80 | MAP4K4 (0.49) | — | |
| SCHEMBL25339743 | 0.79 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL25974745 | 0.78 | KIF11 (0.51) | MAPT | |
| SCHEMBL25973972 | 0.77 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL25340448 | 0.76 | TRPV1 (0.38) | TRPV1 | |
| SCHEMBL25973973 | 0.76 | THRB (0.41) | TRPV1 | |
| SCHEMBL25375442 | 0.75 | FEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |