SCHEMBL25339233

SCHEMBL25339233

Oc1nc(O)c2ccc(-c3nccnc3Oc3ccc(C(F)(F)F)cc3)cc2n1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 16/20 0.39
▸ CSF1R P07333 1/20 0.35
▸ FPR2 P25090 1/20 0.35
▸ SCN9A Q15858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25338741 0.85 TRPV1 (0.45) TRPV1CSF1R
SCHEMBL30544034 0.85 TRPV1 (0.45) TRPV1CSF1R
SCHEMBL25340448 0.80 TRPV1 (0.38) TRPV1
SCHEMBL25340324 0.79 TRPV1 (0.54) TRPV1
SCHEMBL25974745 0.77 KIF11 (0.51) —
SCHEMBL25340961 0.76 TRPV1 (0.45) TRPV1CSF1R
SCHEMBL25973972 0.76 TRPV1 (0.39) TRPV1
SCHEMBL25973973 0.75 THRB (0.41) TRPV1SCN9A
SCHEMBL25375442 0.74 FEN1 (0.38) —
SCHEMBL25973903 0.73 NPC1 (0.39) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146511-A1 COMPOUNDS AND METHODS OF USE THEREOF VIVACE THERAPEUTICS, INC. (US) 2023-08-03 — — WO disclosed
WO-2023146511-A1 COMPOUNDS AND METHODS OF USE THEREOF VIVACE THERAPEUTICS, INC. (US) 2023-08-03 — — WO disclosed
Send feedback