SCHEMBL2534052

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4152465	0.89	VNN1 (0.53)	VNN1GRM4KCNQ3KCNQ2KCNE1
	SCHEMBL14542864	0.77	KCNQ3 (0.65)	VNN1GRM4KCNQ3KCNQ2KCNE1
	SCHEMBL23458490	0.74	KCNMA1 (0.52)	NPC1RAB9AHTTALDH1A1LMNA
	SCHEMBL1923606	0.74	PDE4D (0.42)	VNN1GRM4KCNQ3KCNQ2KCNE1
	SCHEMBL13812239	0.72	LMNA (0.41)	VNN1KCNQ3KCNQ2KCNE1KCNQ1
	SCHEMBL28253118	0.71	S1PR3 (0.46)	VNN1GRM4HTTS1PR3S1PR1
	SCHEMBL20185806	0.70	VNN1 (1.00)	VNN1
	SCHEMBL15867032	0.69	VNN1 (0.56)	VNN1GRM4S1PR3MAPT
	SCHEMBL6869441	0.68	S1PR3 (0.52)	S1PR3S1PR1LMNAS1PR4S1PR2
	SCHEMBL8129368	0.68	MAPK3 (0.44)	VNN1GRM4S1PR3S1PR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.