Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | MPL | P40238 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344718 | 0.76 | KDM4E (0.37) | MPL | |
| SCHEMBL25345643 | 0.72 | TRPA1 (0.35) | — | |
| SCHEMBL21412576 | 0.69 | PDE3B (0.38) | AR | |
| SCHEMBL25345237 | 0.68 | TRPA1 (0.36) | — | |
| SCHEMBL15538013 | 0.68 | MBOAT4 (0.40) | MBOAT4MPLAR | |
| SCHEMBL25203566 | 0.68 | AURKA (0.39) | — | |
| SCHEMBL19813042 | 0.67 | HTT (0.42) | — | |
| SCHEMBL24500129 | 0.65 | AR (0.34) | MBOAT4AR | |
| SCHEMBL26025616 | 0.65 | AXL (0.40) | — | |
| SCHEMBL2198261 | 0.65 | HSD11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4476204-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | Theras, Inc. (US) | 2024-12-18 | — | — | EP | disclosed |
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |