SCHEMBL2535263

SCHEMBL2535263

FC(F)(F)C1(c2ccc(CBr)cc2)N=N1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.42
GABRA1 P14867 3/20 0.38
GABRB3 P28472 2/20 0.38
GABRG2 P18507 1/20 0.38
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
GABRB2 P47870 2/20 0.33
ADORA2A P29274 2/20 0.33
SIRT2 Q8IXJ6 1/20 0.32
ABCB1 P08183 2/20 0.31
ADRA2A P08913 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
NOS1 P29475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31751418 0.84 KIF11 (0.41) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL992639 0.82 GABRA1 (0.47) KIF11GABRA1GABRB3GABRG2TSHR
SCHEMBL18969110 0.82 KIF11 (0.41) KIF11GABRA1GABRB3GABRG2ALDH1A1
SCHEMBL993831 0.82 KIF11 (0.41) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL993942 0.82 KIF11 (0.45) KIF11GABRA1GABRB3GABRG2GABRB2
Hydrochloric Acid SCHEMBL993872 0.80 KIF11 (0.44) KIF11GABRA1GABRB3GABRG2ADORA2A
SCHEMBL17600537 0.80 KIF11 (0.41) KIF11GABRA1GABRB3GABRG2ALDH1A1
SCHEMBL15892710 0.79 ESR1 (0.44) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL18969775 0.79 KIF11 (0.40) KIF11GABRA1GABRB3GABRG2GABRB2
SCHEMBL23860299 0.78 KIF11 (0.45) KIF11GABRA1GABRB3GABRG2GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262615-A1 ANTIOXIDANTS CONTAINING DIAZIRINE FUNCTIONALITIES, COMPOSITIONS COMPRISING THEM AND USE THEREOF BELLARE ANUJ (US) 2025-12-26 WO claimed
US-12312741-B2 Process for dyeing high-performance textiles US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY 2025-05-27 US claimed
US-20250066997-A1 PROCESS FOR DYEING HIGH-PERFORMANCE TEXTILES GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2025-02-27 US claimed
US-11322485-B2 Mass transfer method for light-emitting unit, array substrate, and display device with electro-curable adhesive BOE TECHNOLOGY GROUP CO., LTD. (CN) 2022-05-03 US claimed
US-20210005582-A1 MASS TRANSFER METHOD FOR LIGHT-EMITTING UNIT, ARRAY SUBSTRATE, AND DISPLAY DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-01-07 US claimed
US-10005936-B2 Photoactive bioadhesive compositions NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2018-06-26 US claimed
US-20170137693-A1 ELECTRICALLY ACTIVATED ADHESIVE FOR STRENGTHENING OF A SUBTERRANEAN WELLBORE SCHLUMBERGER NORGE, AS (NO) 2017-05-18 US claimed
WO-2017081325-A1 ELECTRICALLY ACTIVATED ADHESIVE FOR STRENGTHENING OF A SUBTERRANEAN WELLBORE SCHLUMBERGER NORGE, AS (NO) 2017-05-18 WO claimed
US-20150315434-A1 New Photoactive Bioadhesive Compositions NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2015-11-05 US claimed
EP-4251216-B1 SELF-REGULATING BIOADHESIVES FOR WET SUBSTRATES UNIV NANYANG TECH (SG) 2026-05-27 EP disclosed
EP-4003988-B1 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS SERVIER LAB (FR) 2026-05-20 EP disclosed
WO-2026099154-A1 ADHESIVE DEVICE WITH HIGH BONDING STRENGTH TESA SE (DE) 2026-05-15 WO disclosed
WO-2026087555-A1 METHOD FOR PRODUCING PLANAR, POROUS HYDROGELS BY MEANS OF FLOW LITHOGRAPHY DWI - LEIBNIZ-INSTITUT FÜR INTERAKTIVE MATERIALIEN E.V. (DE) 2026-04-30 WO disclosed
US-12527561-B2 Electroceutical patch and catheter system and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-01-20 US disclosed
US-20070098632-A1 Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2007-05-03 US disclosed
US-7145021-B2 Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2006-12-05 US disclosed
US-6693091-B2 CONTAINING PHOTOACTIVE, FLUORESCENT, OR RADIOACTIVE MOIETY THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2004-02-17 US disclosed
US-20030225052-A1 Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2003-12-04 US disclosed
US-20030194370-A1 Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies THE TRUSTEES OF COLUMBIA UNIVERSITY 2003-10-16 US disclosed
WO-2003082185-A2 ANALOGS OF TERPENE TRILACTONES FROM GINKGO BILOBA AND RELATED COMPOUNDS AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2003-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10005936-B2 Photoactive bioadhesive compositions L1CAM, CDH1, PCNA KIF11 2656/4885GABRA1 158/4885GABRB3 524/4885
US-20070098632-A1 Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof GRK5, GPR55, GPBAR1 KIF11 3472/4885GABRA1 630/4885GABRB3 488/4885
US-20030225052-A1 Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof GPBAR1, GRK5, CNR1 KIF11 3870/4885GABRA1 601/4885GABRB3 445/4885
US-12527561-B2 Electroceutical patch and catheter system and uses thereof TMED7, CALD1, ORAI1 KIF11 753/4885GABRA1 1806/4885GABRB3 656/4885
US-20030194370-A1 Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies GRK4, GRK1, GNB1 KIF11 3989/4885GABRA1 1119/4885GABRB3 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.