Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541632 | 0.86 | PAX8 (0.65) | ALDH1A1SMN1; SMN2GAAMAPTCYP3A4 | |
| SCHEMBL2545827 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL4138159 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL2540780 | 0.79 | PKM (0.65) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL2545038 | 0.78 | STAT3 (0.61) | ALDH1A1KMT2AMAPTPAX8LMNA | |
| SCHEMBL2545838 | 0.78 | PAX8 (0.48) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL2536871 | 0.76 | MAPT (0.54) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL2536579 | 0.76 | GRM8 (0.43) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL28466010 | 0.76 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL13785071 | 0.76 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044245-B2 | Method for the preparation of optically active 2-sulfonyloxy-1-phenylethanol derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-10-25 | — | — | US | disclosed |
| US-20100063317-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-03-11 | — | — | US | disclosed |
| WO-2008054155-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063317-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | FOXO1, ENO1, SULT1A1 | ALDH1A1 24/4885SMN1; SMN2 2622/4885KMT2A 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.