Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 7/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374775 | 0.95 | OXTR (0.56) | OXTRAVPR1AGAAMAPTMEN1 | |
| SCHEMBL25379372 | 0.90 | OXTR (0.54) | OXTRAVPR1AGAAMEN1KMT2A | |
| SCHEMBL25377496 | 0.86 | OXTR (0.48) | OXTRAVPR1AMAPTMEN1KMT2A | |
| SCHEMBL25377110 | 0.85 | L3MBTL1 (0.46) | OXTRAVPR1AGAAMEN1KMT2A | |
| SCHEMBL25374942 | 0.79 | L3MBTL1 (0.50) | GAAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL20776699 | 0.76 | OXTR (0.53) | OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL25374455 | 0.74 | TSPO (0.46) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL25376218 | 0.73 | ALDH1A1 (0.42) | GAAKMT2AALDH1A1L3MBTL1POLB | |
| SCHEMBL25378735 | 0.72 | HDAC1 (0.55) | GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL25376544 | 0.72 | TRPM8 (0.42) | MAPTMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |