Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30562908 | 0.81 | HPGD (0.63) | SMN1; SMN2L3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL30567894 | 0.81 | HPGD (0.63) | SMN1; SMN2L3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL21012467 | 0.79 | MMP8 (0.65) | SMN1; SMN2L3MBTL1MMP8CYP2D6TSHR | |
| SCHEMBL7777979 | 0.79 | HPGD (0.64) | SMN1; SMN2L3MBTL1KDM4EPKMPLA2G4A | |
| Hydrochloric Acid SCHEMBL25383162 | 0.77 | LAP3 (0.52) | SMN1; SMN2L3MBTL1KDM4EPKMGPR88 | |
| Hydrochloric Acid SCHEMBL25383156 | 0.77 | LAP3 (0.52) | SMN1; SMN2L3MBTL1KDM4EPKMGPR88 | |
| SCHEMBL25381692 | 0.77 | KDM4E (0.56) | SMN1; SMN2L3MBTL1KDM4EPKMPLA2G4A | |
| SCHEMBL18956515 | 0.77 | HTT (0.57) | SMN1; SMN2L3MBTL1PLA2G4ACES1HPGD | |
| SCHEMBL16254379 | 0.77 | PKM (0.50) | SMN1; SMN2L3MBTL1KDM4EMMP8PKM | |
| SCHEMBL18956313 | 0.76 | PLA2G4A (0.59) | SMN1; SMN2L3MBTL1PLA2G4ACES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693447-B | Ketone amide derivative and pharmaceutical application thereof | 成都威斯克生物医药有限公司 | 2024-08-13 | — | — | CN | disclosed |
| WO-2023165334-A1 | KETO AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 成都威斯克生物医药有限公司 | 2023-09-07 | — | — | WO | disclosed |
| CN-116693447-A | Ketone amide derivative and pharmaceutical application thereof | 成都威斯克生物医药有限公司 | 2023-09-05 | — | — | CN | disclosed |