Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512973 | 0.74 | ALDH1A1 (0.43) | ALDH1A1POLBRXFP1CASP1CASP7 | |
| SCHEMBL30512976 | 0.70 | DUT (0.39) | — | |
| SCHEMBL10485243 | 0.66 | GLS (0.57) | ALDH1A1 | |
| SCHEMBL30057865 | 0.66 | MEN1 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL28540708 | 0.64 | KMT2A (0.34) | ALDH1A1POLBRXFP1KMT2A | |
| SCHEMBL30512910 | 0.62 | ALDH1A1 (0.33) | ALDH1A1POLBRXFP1 | |
| SCHEMBL26948720 | 0.60 | ALDH1A1 (0.45) | ALDH1A1POLBRXFP1KMT2A | |
| SCHEMBL25409117 | 0.57 | DAO (0.41) | ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL21617924 | 0.57 | KDM1A (0.38) | ALDH1A1KMT2A | |
| SCHEMBL1760473 | 0.56 | ALOX5 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138612-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | WO | disclosed |