Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140296 | 0.77 | NOTUM (0.47) | MGLLFGFR1NOTUMIDO1HTR3E | |
| SCHEMBL27939854 | 0.74 | ATM (0.48) | NOTUMCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2222230 | 0.74 | MGLL (0.50) | MGLLFGFR1NOTUMIDO1THRB | |
| SCHEMBL2549234 | 0.74 | ALDH1A1 (0.52) | MGLLNOTUMIDO1ALOX5HTR3E | |
| SCHEMBL8139424 | 0.70 | KDM4E (0.39) | MGLLFGFR1NOTUMIDO1DRD2 | |
| SCHEMBL2547696 | 0.70 | ROCK2 (0.40) | MGLLFGFR1NOTUMIDO1ROCK2 | |
| SCHEMBL2541490 | 0.69 | IDO1 (0.60) | MGLLNOTUMIDO1HTR3EHTR3B | |
| SCHEMBL15328279 | 0.68 | MAPK1 (0.55) | ROCK2PIM1PIM3TP53CYP1A2 | |
| SCHEMBL2548390 | 0.68 | IDO1 (0.50) | MGLLNOTUMIDO1HTR3EHTR3B | |
| SCHEMBL17844118 | 0.67 | FGFR1 (0.49) | MGLLFGFR1NOTUMIDO1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102256961-A | Pyrrole derivatives for use as plant growth regulators | SYNGENTA PARTICIPATIONS AG | 2011-11-23 | — | — | CN | disclosed |
| US-20110263431-A1 | PYRROLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-27 | — | — | US | disclosed |
| EP-2266970-A1 | Substituted aromatic heterocyclic compounds as fungicides | Syngenta Participations AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| US-20100292258-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| CN-101687843-A | Substituted aromatic heterocyclic compounds as fungicides | SYNGENTA PARTICIPATIONS AG | 2010-03-31 | — | — | CN | disclosed |
| EP-2155714-A2 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | Syngeta Participations AG (CH) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008155081-A2 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292258-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | NAT1, NOX1, CBR1 | MGLL 4709/4885FGFR1 206/4885NOTUM 1550/4885 |
| US-20110263431-A1 | PYRROLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | PIN1, PPIE, ALDH18A1 | MGLL 2463/4885FGFR1 558/4885NOTUM 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.