Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584959 | 0.81 | CYP3A4 (0.68) | CYP3A4CYP2C9PTGESALOX5PPARG | |
| SCHEMBL19437161 | 0.81 | CYP3A4 (0.68) | CYP3A4CYP2C9PTGESALOX5PPARG | |
| SCHEMBL19437149 | 0.81 | CYP3A4 (0.68) | CYP3A4CYP2C9PTGESALOX5PPARG | |
| SCHEMBL15263105 | 0.81 | ALOX15 (0.52) | CYP3A4CYP2C9ALOX5HPGDMEN1 | |
| SCHEMBL25424006 | 0.81 | PTGES (0.49) | PDPK1CYP3A4CYP2C9PTGESALOX5 | |
| SCHEMBL16429426 | 0.81 | ALOX15 (0.52) | CYP3A4CYP2C9ALOX5HPGDMEN1 | |
| SCHEMBL1893128 | 0.81 | ALOX15 (0.52) | CYP3A4CYP2C9ALOX5HPGDMEN1 | |
| SCHEMBL25256792 | 0.79 | CYP3A4 (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4CYP3A4 | |
| SCHEMBL25301706 | 0.78 | ALDH1A1 (0.56) | CYP3A4CYP2C9PTGESALOX5PPARG | |
| SCHEMBL25259728 | 0.78 | ALOX5 (0.54) | CYP3A4CYP2C9PTGESALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |