Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336582 | 0.82 | CYP3A4 (0.48) | ALDH1A1CYP3A4ADRB1ADRB2LMNA | |
| SCHEMBL13210667 | 0.81 | ADRB1 (0.38) | ALDH1A1CYP3A4ADRB1ADRB2LMNA | |
| SCHEMBL29290531 | 0.80 | ADRB1 (0.50) | ALDH1A1CYP3A4ADRB1ADRB2LMNA | |
| SCHEMBL13557880 | 0.80 | ADRB1 (0.34) | ALDH1A1CYP3A4ADRB1ADRB2LMNA | |
| SCHEMBL13210655 | 0.80 | ADRB1 (0.34) | ALDH1A1CYP3A4ADRB1ADRB2LMNA | |
| SCHEMBL14486799 | 0.80 | ADRB2 (0.56) | CYP3A4ADRB1ADRB2LMNAHTR1A | |
| SCHEMBL1595637 | 0.78 | CYP3A4 (0.55) | ALDH1A1CYP3A4ADRB1ADRB2LMNA | |
| SCHEMBL11290173 | 0.78 | ALDH1A1 (0.45) | ALDH1A1CYP3A4LMNATSHREIF4A3 | |
| SCHEMBL12889907 | 0.78 | EIF4A3 (0.40) | ALDH1A1LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10346107 | 0.76 | EIF4A3 (0.39) | LMNAEIF4A3ALOX12HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | ALDH1A1 3889/4885CYP3A4 4570/4885ADRB1 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.