SCHEMBL26023939

SCHEMBL26023939

Cc1cc(F)ccc1-c1ccc(C(C)(C)C)c[n+]1C

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.33
MCL1 Q07820 2/20 0.33
PTGS2 P35354 1/20 0.32
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
XBP1 P17861 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NR1D1 P20393 1/20 0.30
HSD11B1 P28845 1/20 0.30
TP53 P04637 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25885896 0.89 ALDH1A1 (0.37) MAPTALDH1A1LMNAGAAMEN1
SCHEMBL26023976 0.86 KIF11 (0.38) MAPTMCL1MEN1MAPK1KMT2A
SCHEMBL25445936 0.84 TSHR (0.39) MAPTALDH1A1LMNAGAANPC1
SCHEMBL26023577 0.84 PTGS2 (0.36) PTGS2
SCHEMBL26345105 0.82 SERPINE1 (0.35) LMNAMEN1NPC1HTTRAB9A
SCHEMBL26023576 0.80 MCL1 (0.36) MCL1NR1D1HSD11B1
SCHEMBL25450386 0.80 TSHR (0.41) MAPTALDH1A1LMNAGAAMEN1
SCHEMBL25884014 0.79 LMNA (0.41) ALDH1A1LMNANPC1RAB9A
SCHEMBL26023964 0.79 ALOX5AP (0.32) MAPTALDH1A1LMNAKCNH2
SCHEMBL26654352 0.79 PTGS2 (0.32) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230309374-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309374-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, SSB MAPT 3611/4885ALDH1A1 1192/4885LMNA 173/4885
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EML4, LBR MAPT 1624/4885ALDH1A1 1467/4885LMNA 108/4885
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 MAPT 4205/4885ALDH1A1 987/4885LMNA 1067/4885
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, OXER1, LBR MAPT 4281/4885ALDH1A1 1046/4885LMNA 509/4885
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OCIAD1, OCIAD2 MAPT 3762/4885ALDH1A1 545/4885LMNA 812/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR MAPT 3654/4885ALDH1A1 1702/4885LMNA 56/4885
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, NR1H2 MAPT 3342/4885ALDH1A1 600/4885LMNA 309/4885
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OCIAD1, OSBP MAPT 1710/4885ALDH1A1 480/4885LMNA 815/4885
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, OXSR1 MAPT 3293/4885ALDH1A1 1603/4885LMNA 548/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR MAPT 3040/4885ALDH1A1 1681/4885LMNA 233/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 MAPT 3599/4885ALDH1A1 569/4885LMNA 2276/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 MAPT 4215/4885ALDH1A1 728/4885LMNA 2023/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 MAPT 178/4885ALDH1A1 2748/4885LMNA 338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.