SCHEMBL25517072

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16499680	0.88	PTPRC (0.46)	CASP3CA12CA9CA1CA2
	SCHEMBL5503121	0.82	CA1 (0.50)	CA12CA9CA1CA2CA7
	SCHEMBL23715181	0.81	ALDH1A1 (0.49)	CA12CA9CA1CA2ALDH1A1
	SCHEMBL17385803	0.80	HSD17B1 (0.48)	CASP3CA12CA9CA1CA2
	SCHEMBL29446230	0.80	SMN1; SMN2 (0.50)	CASP3CA12CA9CA1CA2
	SCHEMBL354166	0.80	SMN1; SMN2 (0.50)	CASP3CA12CA9CA1CA2
	SCHEMBL11249792	0.80	MAPT (0.53)	CASP3CA12CA9CA1CA2
	SCHEMBL22898237	0.80	KDM4E (0.31)	SMN1; SMN2KDM4ETDP1
	SCHEMBL30688575	0.80	TSHR (0.41)	ALDH1A1SMN1; SMN2PDK2KDM4EHSD17B10
	SCHEMBL484748	0.80	PBRM1 (0.51)	CASP3CA12CA9CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.